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Biomedical subjects

C Skorpik

Publications and source records attributed to C Skorpik.

65 records · Page 4Linked to original sources
PubMed1985

[Change in corneal refractive power following artificial lens implantation].

Report on the changes in the corneal refractive power of 284 eyes surgically treated for cataract, in which an IOL had been implanted. The mean corneal refractive power of the eyes was 43.31 +/- 1.43 D preoperatively and 43.39 +/- 1.46 D postoperatively (16th week). The postoperative astigmatism of 215 eyes in which a PCL had been implanted after ECCE was not higher than 1.1 +/- 1.1 D in the 16th postoperative week after selected removal of the nylon sutures. This study demonstrates that there is no statistically significant change in the mean corneal refractive power after cataract surgery with IOL implantation.

Astigmatism↗
PubMed1984

Inhibition of experimental intraocular proliferation with intravitreous 5-fluouracil. A transmission electron-microscopic study in rabbits.

5-Fluouracil, administered at concentrations of 1 and 5 mg to inhibit experimental intraocular proliferation produced by intravitreously implanted fibroblasts in rabbits, produced tissue alterations revealed by TEM. The degranulation and migration of pigment epithelial cells, the incipient degradation of axons and myelin sheets, the migration of glial cells and the prominent edema of the inner layers indicated a non-negligible damage to the retina, suggesting to abstain from its use in human eyes and to search for less neurotoxic drugs, possessing the same inhibitory effect on intraocular proliferation.

Animals↗
PubMed1983

[Severe changes in the fundus oculi in pregnancy toxemia. 3 cases].

Three cases of severe retinal changes in conjunction with EPH gestosis are presented. 2 patients showed 4th degree hypertensive fundus changes (Keith-Wagener classification) and one suffered from bilateral exudative retinal detachment after an eclamptic fit in the 32nd week of pregnancy. The possible causes of retinal changes and visual disturbances in EPH gestosis are reviewed.

Adult↗
PubMed1983

Inhibition of experimental intraocular proliferation with intravitreal 5-fluouracil.

5-Fluorouracil was used to inhibit experimental intraocular proliferation in rabbit eyes, produced by homologe fibroblast implantation. Two different concentrations were used, 1 and 5 mg in a single intravitreal injection. The eyes were followed up over 4 weeks. Proliferation and resulting traction detachment was reduced from 75% to 30% in the 1-mg 5-fluouracil group. In addition, we observed retinal and vascular changes in a considerable number of eyes treated with 1 mg and much more pronounced alterations in most of the eyes treated with 5 mg fluouracil.

Animals↗
PubMedDate not supplied

Long-term course of induced astigmatism after clear corneal incision cataract surgery.

PURPOSE: To determine whether a small clear corneal temporal incision produces less surgically induced astigmatism than a larger incision. METHODS: One hundred three consecutive cases of postoperative astigmatism after clear corneal incision cataract surgery were studied for a minimum of 1 year. Only self-sealing incisions from the temporal side were made as follows: 3.2 mm (Group A); 4.0 mm (Group B); 5.2 mm (Group C). We considered the amount and axes of the keratometric readings at different times as well as their course over time. Induced astigmatism was calculated using three methods. Axial changes were also analyzed. RESULTS: Immediately after the surgery, there was a small, surgically induced, with-the-rule astigmatic shift in all groups, which in most cases decreased to near preoperative levels with time. One year postoperatively. mean induced astigmatism was 0.09 diopter (D) in Group A, 0.26 D in Group B, and 0.54 D in Group C. Most cases had minimal axial changes. In Group A, 86% had an axial change of fewer than 30 degrees; in Group B, 76%; and Group C, 73%. CONCLUSIONS: The smallest incision group had the least surgically induced astigmatism and axial change. All incision groups remained stable and had satisfactory clinical results.

Astigmatism↗