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Biomedical subjects

C T Nagoshi

Publications and source records attributed to C T Nagoshi.

47 records · Page 3Linked to original sources

The flushing response to alcohol use among Koreans and Taiwanese.

Alcohol use, the existence of a flushing response to alcohol and the amount of alcohol required to evoke flushing were studied by questionnaire in 87 homeland Korean and 101 Taiwan Chinese families. SFs (slow flushers--flush after two or more drinks) and FFs (fast flushers--flush after one drink or less) were compared. Despite the similarity in the proportions of subjects who reported flushing, Koreans reported very heavy and Taiwanese very light alcohol use. The two groups differed substantially in the proportions of SFs and FFs. Five ethnic groups in Hawaii were compared with the Koreans and Taiwanese. It appears that fast flushing, but not slow flushing, leads to substantial decreases in alcohol use among all seven groups. The association of flushing type with the extent and duration of flushing and with the frequency of other alcohol-related symptoms may be dose-dependent. For both Koreans and Taiwanese, family resemblances in flushing are substantial but not supportive of the belief that flushing is dominant and results from the influence of a single autosomal gene pair. Of the large groups of subjects from whom data were obtained (Caucasians, Chinese, Filipinos, Hawaiians or part Hawaiians, and Japanese in Hawaii; homeland Koreans; and Taiwan Chinese), the Koreans and Taiwanese differ the most from one another in alcohol consumption. In summary, there is substantial diversity among groups frequently lumped together as "Mongoloid."

Adult↗

Asians, Asian-Americans and alcohol.

The association of flushing (vasodilation, reddening of the skin) with the alcohol use of Asians and Asian-Americans is examined. Historical changes in alcohol use, recent secular changes in alcohol use, and marked differences in consumption among Asian populations and among Asian-Americans of the same national origins, as well as the lack of reduction of sex differences among flushers, indicate that flushing has little influence on alcohol consumption. Social, psychological, and cultural influences seem to be more adequate explanatory devices with regard to Oriental alcohol use.

Alcohol Drinking↗

A longitudinal study of family practice residents' attitudes toward alcoholism.

BACKGROUND AND OBJECTIVES: This study sought to analyze whether the experience of residency training at a public hospital where alcoholism is highly prevalent, combined with a didactic program emphasizing community resources, would result in changes in residents' baseline attitudes. Previous research has suggested that alcoholism-related attitudes are therapeutically important. METHODS: Forty-three family practice residents took the Marcus Alcoholism Questionnaire at the beginning, and at the end, of their 3-year training program. Initial scores were compared with an "expert" sample (Toronto Alcohol and Drug Research Foundation). Residents' initial and final scores were also compared. RESULTS: Residents' entry attitudes were similar to those of the "expert" sample. On six of nine scales, there were no significant changes between entry and exit attitudes. At final testing, however, residents were significantly more likely to agree that a periodic excessive drinker can be an alcoholic (t = -3.15, P < .01), that alcoholism is not an illness (t = -2.57, P < .05), and that alcoholism is a harmless voluntary indulgence (t = 2.08, P < .05). However, exit means for the latter two scales still remained in a functional category, when compared with the expert sample. CONCLUSIONS: Resident attitudes did not show any substantial deterioration during the course of training. The structured curriculum emphasizing community resources and positive role models may have counterbalanced the frustrations of the clinical training site.

Adult↗