PubMed Health⌕ Search

Biomedical subjects

C Witting

Publications and source records attributed to C Witting.

29 records · Page 2Linked to original sources
PubMed1977

Immunofluorescence studies on formalin-fixed and paraffin-embedded material.

In an attempt to apply immunomorphologic techniques to formalin-fixed material, various tissues were studied by indirect immunofluorescence. To minimize nonspecific background staining, formalin-fixed paraffin sections were treated with pronase prior to incubation with the antisera. This technique was published by Huang in 1975 to study hepatitis B core and surface antigen in formalin-fixed liver-tissue. Our examination demonstrate that this technique might enable the morphologist to identify immunoglobulins in formalin-fixed tissues and so to get new criteria for their diagnosis.

Adult↗
PubMed1977

[Gastrointestinal sarcomas].

In 45 primary sarcomas of the gastrointestinal tract the authors attempt to derive criteria for prognosis from histology and localization of the tumors and from clinical parameters. Their observations lead to the conclusion that 1) proximal sarcomas of the gastrointestinal tract have a better prognosis than distal sarcomas, 2) lymphocytic malignant lymphomas has a better prognosis than other histologic types, and 3) there is a correlation between blood sedimentation rate and prognosis.

Adolescent↗
PubMed1976

Immunofluorescence studies on pathologic routine material: application to malignant lymphomas.

In an attempt to apply immunmorphologic techniques to pathologic routine material, malignant lymphomas of the Non-Hodgkin- and the Hodgkin-type were studied by indirect immunofluorescence. To minimize nonspecific background staining formalin fixed paraffin sections were treated with protease prior to incubation with the antisera. The usefullness of this procedure in providing additional diagnostic criteria was tested on specimens of malignant lymphomas (chronic lymphocytic leukemias, immunocytic lymphomas, plasmocytic lymphomas, centrocytic lymphomas, centroblastic-centrocyctic lymphomas, centroblastic lymphomas, immunoblastic lymphomas, lymphoblastic lymphomas of Burkitt, convoluted and unclassified type, Hodgkin's disease). In addition, cases of nonspecific lymphadenitis were studied. The discrimination of single cells particularly of the B-cell line was facilitated using immunofluorescence and different patterns were easily recognized thus aiding the diagnosis based on light microscopic criteria. In addition, preliminary evidence was obtained that lymphoblastic lymphomas categorized as "others" may be further characterized.

Fluorescent Antibody Technique↗
PubMed1976

[Amyloid tumors in soft tissues of the neck].

Tumorous amyloid deposits in the neck region of a 31-year-old man caused difficulties in the preoperative differential diagnosis of a tumorous process of the thyroid gland. Several tumorous amyloid deposits compressing and eroding the left nevus vagus and having no connection to the trachea or thyroid gland were removed. Such isolated tumorous amyloid deposits in the neck region have not been described before. Histologically no thyroid tissue was found. A medullar cancer of the thyorid gland that has to be excluded in such cases was not found.

Adult↗
PubMed1975

[Correlation of splenomegaly and blood picture changes in graft vs host reaction of the mouse].

The early phase of graft-versus-host-reaction is characterized by a rapid decline of lymphocytes in the peripheral blood, with a minimum between days 9 and 11, and return to normal until day 20 after spleen cell grafting. Erythrocytes and hematocrit do not change during this period. There is no causal correlation between splenomegaly and lymphopenia. Lymphopenia provides a criterium for experimental graft-versusu-host-reaction equivalent to the spleen-index.

Animals↗
PubMed1975

Morphological and biochemical findings in a case of mucopolysaccharidosis type III A (Sanfilippo's disease type A).

Morphological and biochemical autopsy findings of a 12 year old girl with mucopolysaccharidosis type III (Sanfilippo's syndrome). The clinically suspected diagnosis was biochemically ascertained before the patients death. The autopsy findings obtained by biochemical and by light and electron microscopic investigations of different organs are compared with the results of other authors.

Autopsy↗
PubMed1975

[Dracunculosis].

Explore the source record for details and available documents.

Adult↗
PubMedDate not supplied

[Morphology of yttrium-90 treated experimental arthritis].

A rheumatoid arthritis was produced in rabbits according to the method described by Klinge. It was treated with a single dosage of 2 mCi Yttrium-90. After 3 weeks the animals treated with Yttrium showed less fibrosis of the synovial membrane than the controls. After 6 weeks the synovial membrane of the non-treated controls showed considerable fibrosis but the synovial villi of the treated animals were slender and largely unchanged.

Animals↗