Acute systemic immediate hypersensitivity in the pig.
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Biomedical subjects
Publications and source records attributed to D A Pass.
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Studies on the site of proliferation of Pasteurella haemolytica in the bovine nasal cavity have been carried out.P.haemolytica were isolated from 15 selected major anatomical areas of the nasal cavity in calves with high numbers of P.haemolytica following shipment from Western Canada. When the organisms were present in the nasal cavity of live animals in low numbers, they were isolated from many, but not all, areas. P.haemolytica was isolated post mortem from one or more selected areas of several nasal cavities in spite of negative antemortem cultures. By the direct fluorescent antibody technique, P.haemolytica was demonstrated at the surface of nasal epithelial cells. Organisms were not seen in or between epithelial cells nor in the ducts nor alveoli of glands. The findings were similar when high and low numbers of P.haemolytica were present in the nasal cavity.
Aspects of the histology of the nasal mucosa of calves from four to six months of age have been described. The functional significance of the type of epithelium, its thickness, the degree of neutrophil invasion, and its relationship to the numbers of Pasteurella haemolytica in the nasal cavity have been discussed. In addition, the arrangement and depth of glands in the lamina propria and the presence of lymph follicles have been described.
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The incidence and severity of tibial dyschondroplasia in broiler chickens were increased by feeding rations containing high levels of phosphorus relative to the level of calcium. Tibial dyschondroplasia was not eliminated by feeding a ration containing 1.5% calcium and 0.5% available phosphorus. Before typical dyschondroplasia developed, chickens fed a high level of phosphorus had uniformly thickened growth plates at 2 weeks of age. The majority of this thickening was due to an increase in the zone of proliferation, identical to that which occurs in calcium-deficiency rickets.
The microscopic lesions in the nasal cavity, nasal bones, and infraorbital sinuses of five budgerigars with chronic upper respiratory tract infection are described. All five had chronic inflammation of the lining of the air spaces within the bones surrounding the nares and infraorbital sinuses.
The lesions associated with a papova-like virus infection in two splendid parakeets (Neophema splendida) are described. The most obvious microscopic lesion in both birds was enlargement of renal medullary collecting-duct epithelial cells. The nuclei of these cells were also enlarged, pleomorphic, and often bizarre, and intranuclear and intracytoplasmic virus-like particles (48 nm in diameter) were demonstrated within them. One bird also had a hepatopathy characterized by hepatocyte enlargement and nuclear pleomorphism.