The effect of thiabendazole on Dictyocaulus viviparus in experimentally infected calves.
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Animals↗
Biomedical subjects
D B Ross
Publications and source records attributed to D B Ross.
The gold standard for atrial septal defect closure: current surgical results, with an emphasis on morbidity.
Device closure of atrial septal defects (ASDs) is rapidly becoming routine in children. Comparisons are often made to older surgical series with higher morbidities. However outcomes including reintervention, late failure, and the need for long-term follow-up must be considered and compared to those of a current surgical series. One hundred consecutive surgical closures of ASDs in children were reviewed. The mean age was 60.5 +/- 6.4 months; 6 patients underwent repair in the first year of life. Full clinical and echocardiographic follow-up was available on all patients. There was no mortality; there were no residual ASDs and no neurological complications. There were 3 cases of postpericardiotomy syndrome and 26 pericardial effusions. Median stay was 4 days; all patients have been discharged from follow-up. A review of the literature on the short-term follow-up of ASD devices revealed a number of problems. Their long-term durability is unknown. As such, it remains an experimental procedure and must be compared over the long-term to the current gold standard, surgical repair.
Adolescent↗
St. Jude SPV versus Medtronic Freestyle: a single institution comparison of two stentless aortic valves.
BACKGROUND: Improved hemodynamics with the SPV and Freestyle bioprostheses compared to stented valves have been reported. It has been suggested that there is more aortic insufficiency (Al) with the Freestyle than with the SPV valve. This study was designed to assess the hemodynamic performance of these two valves implanted at a single institution with all echocardiograms reviewed by one echocardiographer. METHODS: From 1993 to 1997 112 patients underwent aortic valve replacement with stentless aortic valves (69 SPV, 43 Freestyle). There were no major preoperative differences in patient age, gender, NYHA class, or ejection fraction between groups. Echocardiographic assessment was obtained at discharge, 3 to 6 months following surgery, and yearly thereafter. RESULTS: Mean follow-up was 15.9 months for the SPV and 28.6 months for the Freestyle. Both valves have excellent valve areas and low transvalvar mean gradients. There is a trend for more Al in the SPV group. At 1 year, 1+ or greater Al was present in 11 of 42 SPV patients compared to 2 of 34 Freestyle patients (p = 0.030). Al has tended to remain stable over time, has not progressed, and is not clinically evident. DISCUSSION: Differences in the previously reported incidence of aortic insufficiency with these valves may have more to do with the method of reporting Al than its actual frequency. Within our institution, there has been slightly more mild Al with the SPV valve than with Freestyle. Long-term follow-up of these valves is needed to determine if the Al progresses or becomes clinically important. To date there is no such trend with either valve.
Adult↗