[Intravenous acyclovir (ACV, Zovirax) therapy of varicella zoster infections in immunologically endangered patients].
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Acyclovir↗
Biomedical subjects
D Bridgen
Publications and source records attributed to D Bridgen.
Acyclovir tolerance in humans.
Acyclovir tolerance has been explored in a broad range of human populations and dosage regimens with intravenous, topical, and oral formulations. Phase I pharmacokinetic/tolerance studies assured safety in special populations at unique risk of complicated herpes infections who were simultaneously at increased risk of toxicity to anti-DNA chemotherapeutic agents. Further safety evaluations accompanied placebo-controlled Phase II studies in infected patients who represent future users of acyclovir. These studies confirm acyclovir as the safest antiherpes agent to be explored in clinical studies to date.
Acyclovir↗
Transient renal impairment during intravenous acyclovir therapy.
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Acyclovir↗