[Biological characteristics of fibronectin and its role in wound healing].
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Animals↗
Biomedical subjects
D C Zhong
Publications and source records attributed to D C Zhong.
[Median thoracic flap with cartilage for repair of large tracheal defect].
Large defect of the tracheal wall is very difficult to repair without support of cartilage. Two patients with large defect of the tracheal anterior wall (2.5-3.0 x 6.0 cm) were treated successfully. For the patients with much scar in neck a median thoracic flap (3.5 x 4.0 x 7.0 cm) was designed as follow: The flap was elevated, and 3 autocartilage bows (0.5 x 0.4 x 0.4 cm) were implanted into the separated tunnels just beneath the subdermal vascular plexus of the flap. The flap was sutured at the border of tracheal wall defect. The cartilage bows were fixed and covered with a combined cervico-thoracic and cervico-acromial bilobate flap. 13 cadavers showed that 1-2 stem vessels (n = 9) or 4-5 vascular branches (n = 4) developed in the flap.
Adult↗
[Biliogenic liver abscess caused by acute obstructive suppurative cholangitis].
Biliogenic liver abscess was found by autopsy in 52 of 61 (85.2%) cases died of acute obstructive suppurative cholangitis (AOSC) at our hospital from 1957 to 1980. Of the 52 cases with liver abscess, 44 (84.6%) had multiple abscesses and 47 (90.4%) suffered complications of the rupture of liver abscess. Liver abscess was clinically diagnosed in only 7 of 52 cases who underwent emergency operation, with the predeath definite diagnosis of 13.5% (7/52). The authors considered biliogenic liver abscess an inevitable outcome not an accidental complication of AOSC when the high pressure in bile duct could not be relieved, and emphasized the importance of prevention, early diagnosis and treatment of liver abscess in order to decrease the mortality of AOSC.
Acute Disease↗
Anticancer gelatin microspheres with multiple functions.
Biodegradable, hydrophilic gelatin microspheres (GM) with an average diameter of 70 microns were prepared by cross-linking gelatin with glutaraldehyde for hepatic intra-arterial infusion. An anticancer agent, mitomycin C (MMC), together with a radioisotope, 131I, were bound to the GM for chemotherapy and local internal radiotherapy. The 131I-labelled MMC-GM (131I-MMC-GM) could accumulate in the specific site and embolize the hepatic arteries after the hepatic intra-arterial infusion, while it caused various effects to the liver cells. The 131I-MMC-GM remained within the hepatic arteries for at least one month. In vitro release of drugs from the GM was also quantified using a dynamic dialysis method.
Animals↗
[Effect of porto-azygous disconnection with or without low esophageal transection on esophageal varices and portal pressure].
73 cases of cirrhotic portal hypertension treated in 4 years period (1982-1986) were followed by endoscope. Varices showed very little chance to disappear completely, and little difference in results between porto-azygous disconnection and that in combination with lower esophageal transection. The pressure of disconnected coronary vein on stomach side showed considerable elevation than that before and also in combination with lower esophageal transection. Continuous observation of portal pressure changes during and after operation for 4 days showed variations of amplitude suggesting redistribution of portal circulation. Judging from the series of postoperative events in follow-up, particularly rebleeding from recurrence of varices, there was renewed collateral circulation developed in the area of porto-azygous connection irrespective of the means of interruptions.
Azygos Vein↗