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Biomedical subjects

D Chassagne

Publications and source records attributed to D Chassagne.

At least 73 records · Page 4Linked to original sources
PubMed1977

[The practical application of computer dosimetry in gynaecological radiotherapy. 1,200 cases studied between 1968 and 1976 of the Gustave-Roussy institute (author's transl)].

Experience gained since 1970 by the study of 1,200 cases in which computerised dosimetry was used has led to the proposition of a reliable and useful method. The results are expressed per 24 hours of exposure in numerical form with regard to reference points, as well as in the form of drawn isodose curves in three different planes of reference: sagittal, frontal oblique by sources and frontal oblique passing by the plane of pelvic lymphatics. The authers recall the definition of reference points: bladder, rectum and pelvic walls. Using three typical examples, the aid provided by dosimetry is described. The concept of a "radiotherapy identity card" as a means of expressing the dose given is discussed. Comparison between dosimetric results and the results of treatment is encouraging in terms of the continued and fore general use of the method.

Cesium Radioisotopes↗
PubMed1977

[Endocurietherapy for carcinoma of the penis (author's transl)].

46 cases of epithelioma of the penis treated by endocurietherapy (Iridium 192) are analysed, with a minimum follow up to of 5 years. The local results appear to be excellent for small lesions, of the order of 20 mm, with only 2 recurrences out of 14 cases. With a slight potential of lymphatic spread, 12 of the patients are apparently cured. The organ has been preserved in perfect functional state. More extensive lesions, but less than 40 mm in size, have a less satisfactory prognosis by virtue of more frequent lymph node spread, difficult to control, and their general course. However local results remain quite respectable, despite 5 recurrences out of 25 cases, 3 of which were easily "salvaged" by surgery. 12 of these patients are apparently cured and in 9 the organ has been preserved in satisfactory functional condition. By contrast, massive forms, larger than 40 mm, recur or necrose and thus represent a poor indication for curietherapy. In conclusion it may be said that endocurietherapy for carcinoma of the penis, by virtue of a technique rendered opitmal by accurate prior dosimetry, is certainly an excellent therapeutic option for all small or moderately extensive lesions, avoiding mutilation. The presence of lymph node involvement has an unfavourable influence on prognosis.

Humans↗