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Biomedical subjects

D Dumitrescu

Publications and source records attributed to D Dumitrescu.

At least 19 recordsLinked to original sources

[Hepatitis beta-antigen titer and subtypes of acute and chronic hepatitis].

The incidence of the hepatitis B antigen (HBSAg) in the sera of 650 acute virus hepatitis (AVH) and 200 chronic hepatitis (CH) patients was determined by screening test (counter-immunoelectrophoresis and immunodiffusion). The findings showed a positivity in 28% of the acute virus hepatitis patients and in 47% of the chronic hepatitides. Further, the detected HB Ag was investigated both quantitatively (titer) and qualitatively (subtype). The results obtained have shown the absence of differences in the HB Ag-titer distribution of the two groups investigated and the prevalence of the HBSAg/ayw subdeterminant in both groups (62% in AVH and 57% in CH patients).

Acute Disease↗

Applicability of the leukocyte migration inhibition test in the clinical practice.

The leukocyte migration inhibition test reveals in vitro the presence of lymphocyte sensitivity and, consequently, of cell-mediated immunity, to a given antigen. Applied in a variety of immune and allergic cases it proved to be useful for the positive diagnosis of the disease and/or for the detection of cell-mediated immune deficiency. The results obtained recommend the leukocyte migration inhibition test in the clinical practice.

Cell Migration Inhibition↗

[Condensing osteitis of the middle third of the clavicle].

A total of 16 cases only have been reported in the world specialized literature. This is a new case, of a patient aged 20 years, a male working in the metallurgical industry. This is the first case reported in our country. Clinically the patient presented a painful global swelling of the median third of the clavicula on the left side. Biological constant were normal. Radiographic investigations revealed an increase in volume and a condensation of the median part of the clavicula, and scintigraphical studies revealed an intense incorporation of the radioisotope. Histopathologic studies showed lamellar and spongious bone tissue, with a normal trabecular structure, although considerably thickened. Data for the differential diagnosis are presented, and in the first place those concerning intra-sterno-clavicular hyperostosis, sterno-costo-clavicular arthrosis, chronic subacute osteitis, avascular necrosis of the clavicular epiphysis (Friedrich disease), and Tietze syndrome. The etiopathogenesis of this rare benign clinico-radiologic entity remains unknown.

Adult↗