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Biomedical subjects

D Dumitrescu

Publications and source records attributed to D Dumitrescu.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

The value of cimetidine in the treatment of gastroduodenal ulcer.

The therapeutic effects of 1 g/day cimetidine in short-term courses of 21 days have been tested by a double blind study in 20 patients, of which 17 with duodenal ulcer and 3 with both gastric and duodenal ulcerations, in comparison with a similar group of patients who received placebo. The symptomatology was characteristic in all the cases, X-ray presence of ulcer in 17 patients and indirect signs in 3, endoscopic examination positive. The total volume of ClH nocturnal secretion, as well as the basal and maximal hydrochloric secretions decreased, but the differences with respect to the initial values were not statistically significant; the inhibition of gastric acid secretion by cimetidine amounted to 40%; ulcer healing was noted in 3 out of 17 cases. The adverse effects were rare: sleeplessness in 6 cases, asthenia in 4, dry mouth in 3. The differences between the results of cimetidine administration and those in the placebo group had no statistical significance. It is concluded that a short-term course of 21 days is not sufficient to obtain healing of the gastric or duodenal ulcerations.

Adult↗
PubMedDate not supplied

[Total denervation in painful diseases of the hip].

The authors discuss, on the basis of 16 cases, the results obtained by the total denervation of the hip in the painful affections, of various origins, of this area. The best results have been obtained in painful coxarthroses secondary to luxating dysplasia of the hip, and the least satisfactory in the rheumatic affections.

Denervation↗
PubMedDate not supplied

[Osseous desmoid fibroma (2 case reports)].

Bone dermoid fibroma, described by Jaffe in 1958 is a benign fibroblastic tumour characterized by a remarkable tendency to expansion and to local recidives, without metastasizing. Some 38 cases have been reported to the present in the specialized literature. Two new cases are reported now, the first in the Romanian medical literature, one with localization of the tumour in the superior tibioperoneal metaphysis, and another located in the inferior femoral metaphysis. The first case recidivated after 3 surgical exereses over a period of nearly two years, and had to be amputated. The second case was solved by resection-arthrodesis of the Juvara-Merle d'Aubigne type, and is currently followed-up.

Adult↗