PubMed Health⌕ Search

Biomedical subjects

D E Raeside

Publications and source records attributed to D E Raeside.

At least 19 recordsLinked to original sources

Orthovoltage radiation therapy treatment planning using Monte Carlo simulation: treatment of neuroendocrine carcinoma of the maxillary sinus.

Dose distributions that result from treating a patient with orthovoltage beams are best determined with a treatment planning system that uses the Monte Carlo method, and such systems are not readily available. In the present work, the Monte Carlo method was used to develop a computer code for determining absorbed dose distributions in orthovoltage radiation therapy. The code was used in planning treatment of a patient with a neuroendocrine carcinoma of the maxillary sinus. Two lateral high-energy photon beams supplemented by an anterior orthovoltage photon beam were utilized in the treatment plan. For the clinical case and radiation beams considered, a reasonably uniform dose distribution (+/- 10%) is achieved within the target volume, while the dose to the lens of each eye is 4-8% of the prescribed dose. Therefore, an orthovoltage photon beam, when properly filtered and optimally combined with megavoltage beams, can be effective in the treatment of cancers below the skin, providing that accurate treatment planning is carried out to establish with accuracy and precision the doses to critical structures.

Humans↗

Designing, benchmarking, and applying a Monte Carlo electron transport code.

The design of a Monte Carlo electron transport code is described, with particular attention being given to the modeling of multiple-scattering, ionization, and bremsstrahlung production. Comparisons of code predictions with experimental data are presented, together with simple radiation therapy applications.

Child↗

Removal of streaking artifact in computed tomography.

In transmission computed tomography, relative X-ray attenuation measurements are made at various angles around a patient's body. These input projection data are reconstructed to yield a cross-sectional view of internal structure. If the body section contains material that severely attenuates the X-ray beam (e.g., surgical clips, lead fragments), high-density streaks that obliterate internal structure will be produced in the process of image reconstruction. This loss of diagnostic information renders the scan useless. A technique has been developed that removes this imaging artifact. The approach views the affected projection data as misinformation. These data are assigned new values, and image reconstruction is performed without changing existing computer hardware or software. Projection data for a head section containing a lead fragment were obtained by Monte Carlo simulation. Three methods of obtaining replacement data were examined. A nearest-neighbor pattern recognition technique yielded excellent results.

Humans↗

Optimal radiotherapy treatment planning for carcinoma of the cervix uteri.

A study is described in which an optimal time-dose-fractionation (TDF) value for radiotherapy of carcinoma of the cervix uteri is found using clinical data for points 2 cm from the cervical os proximally along the direction of the cervical canal and 2 cm laterally to the canal. The optimal TDF value was found to be 127 +/- 10 for regimens utilizing external beam cobalt 60 irradiation (or external irradiation of equivalent quality) in combination with intracavitary radium irradiation.

Female↗

A pattern recognition method for the removal of streaking artifact in computed tomography.

A new method is presented for the removal of streaking artifact in computed tomography. The method uses a nearest-neighbor pattern recognition technique to redetermine ray sums that intersect the foreign object responsible for the streaking. When the method is applied to the removal of streaking artifact caused by lead in a skull phantom, excellent results are obtained.

Models, Structural↗

A formalism for the assignment of uncertainties to clinical probabilities of hypothyroidism, euthyroidism, and hyperthyroidism.

A formalism for the optimal estimation of the probabilities of hypothyroidism, euthyroidism, and hyperthyroidism is outlined. The scheme provides a means for assigning uncertainties to the estimates. These uncertainties can be used to determine whether or not the difference between two probabilities is statistically significant. Clinical data are utilized to illustrate the method.

Computers↗

Fourier analysis of the echocardiogram.

Fourier analysis has been applied to the analysis of echocardiograms, with the result that anterior mitral leaflet waveforms have been classified in a manner which is unambiguous and which lends itself easily to present-day automated technology.

Echocardiography↗

A generalization of Chevrot's method for determining anteversion and cervico-diaphyseal angles.

Chevrot's method for determining the angle between the axis of the femoral shaft and the axis of the femoral neck (the cervico-diaphyseal angle), and the angle between the axis of the femoral neck and the diacondylar plane (the anteversion angle) has been investigated and generalized. Mathematical formulae giving the anteversion and cervico-diaphyseal angles in terms of two x-ray tube angles and two measured projections of the cervico-diaphyseal angle have been derived. These formulae facilitate preparation of computer programs and tables for the routine clinical determination of the anteversion and cervico-diaphyseal angles.

Femur↗

A study of the dose to the thyroid and the eye in computed tomography of the brain.

Thermoluminescent dosimeters were used to estimate the dose to the thyroid and the eye for routine clinical computed tomography of the brain using an EMI CT5005 scanner (20-sec data acquisition mode, bolus covering the head). The data can be summarized by the linear relations Dt = (7.5 +/- 0.8)N millirads (8 less than or equal to N less than or equal to 18) and De = (39 +/- 5)N + (1400 +/- 200)n millirads (8 less than or equal to N less than or equal to 20, 0 less than or equal to n less than or equal to 6) where Dt is the dose to the tissue anterior to the thyroid, De is the dose to the anterior tissue of the eyelid, N is the total number of CT cuts, and n is the number of cuts in which the globe of the eye is imaged.

Eye↗

Toward the automation of echocardiography.

Schemes applicable to the automated classification of disease states identifiable through echocardiography are being studied. Initial success has been achieved in the classification of anterior mitral leaflet wave forms associated with mitral stenosis and mitral valve prolapse. These two categories were found to be readily distinguished from the normal state in a Fourier analysis framework.

Automation↗

Central axis depth dose for a 2.5 MV Van de Graaff generator.

Central axis percentage depth dose values and isodose curves for the bremsstrahlung beam from a 2.5 MV Van de Graaff generator were measured with a water phantom at 100 cm target-to-surface distance. Tissue-air ratios were calculated from the central axis depth dose data. Use of the 2.5 MV percentage depth dose values are necessary for treatment planning since they are substantially larger than the values given in compilations for 2.0 MV beams.

Humans↗

The application of pattern recognition techniques in the analysis of metacarpophalangeal lengths.

Pattern recognition techniques have been applied to the analysis of metacarpophalangeal lengths obtained from hand radiographs. A data base consisting of healthy subjects, and subjects exhibiting achondroplasia, Down's syndrome, and Turner's syndrome was studied. A classification technique was found which effectively separates these conditions. The technique is suitable for computer automation.

Achondroplasia↗

Bayesian statistics: a guided tour.

An overview of Bayesian statistical decision theory is presented in the tutorial spirit. A section on fundamental principles is followed by selected applications of the Bayesian approach to parameter estimation, pattern recognition, image processing, computer-aided medical diagnosis, optimal diagnostic test selection, and radiotherapy treatment planning.

Decision Making↗