[Villous adenoma of the stomach].
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Biomedical subjects
Publications and source records attributed to D Gaitini.
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Four cases of gastric villous tumors are presented. The radiologic features of these rare tumors in the stomach are described. Their high propensity for malignancy as compared to villous adenoma of the colon is emphasized. In 2 of 4 of our patients the villous tumors were malignant. The radiologic picture of villous tumors of the stomach is characteristic enough to suggest the diagnosis.
The contribution of high-resolution real-time ultrasonography to the diagnosis of deep vein thrombosis (DVT) was evaluated in a prospective study performed on 96 patients. 45 patients were also examined with contrast venography and 79 with continuous wave Doppler ultrasound. The femoral and popliteal veins were examined for compressibility by pressure with the transducer probe, response to deep inspiration and Valsalva's manoeuvre and presence of an intraluminal mass. The contralateral veins were routinely screened for comparison. The diagnostic sensitivity versus phlebography was 87%, and the specificity 100% for the femoral vein. When including the popliteal vein the specificity was 91%. Real-time ultrasonography together with Doppler ultrasound examination is an effective non-invasive approach for the diagnosis of DVT. Phlebography can be avoided if these two examinations are unequivocally positive or negative for DVT.
Thrombosis of the internal jugular and subclavian veins was demonstrated by high-resolution real-time ultrasonography in eight patients. The sonographic findings were an intraluminal mass of low or mild amplitude echoes, loss of respiratory rhythmicity and venous pulsation, absence of vein response to respiratory maneuvers (Valsalva and sniff test) and incompressibility of the thrombotic jugular vein. Follow-up examinations after anticoagulant and local streptokinase therapy allowed monitoring of the treatment. High-resolution ultrasonography is a useful noninvasive technique for the diagnosis and follow-up of therapy in thrombosis of the jugular and subclavian veins.
Thickening of the gallbladder wall in patients with ascites has been attributed not to the presence of ascites but to the associated hypoalbuminemia. The contribution of hypoalbuminemia was examined by sonographically measuring the thickness of the gallbladder wall in 12 patients with chronic renal failure who were on peritoneal dialysis. All patients had hypoalbuminemia, with serum albumin levels of 2.2-3.3 g/dl (normal range, 3.5-5.0 g/dl). In all patients, the thickness of the gallbladder wall was within the normal range of less than 3 mm. In the patients studied, hypoalbuminemia was not a cause of thickening of the gallbladder wall even when peritoneal fluid was present.
Hydatid disease is endemic in certain villages in Galilee, Israel. Most patients seen in our thoracic surgical department have only pulmonary cysts, but some of them have concomitant liver cysts. From 1963 until 1982, 10 patients who were referred for lung operations had echinococci removed from the liver through a right thoracotomy. Every patient with a suspected diagnosis of pulmonary hydatidosis had isotope and ultrasound scans of the liver. Liver cysts found adjacent to the right hemidiaphragm were removed at thoracotomy. Patients having liver cysts remote from the diaphragm were referred for laparotomy. There were no postoperative complications or deaths in this series. We advocate routine search for liver cysts in any surgical candidate with lung hydatids. Accessible liver cysts should be excised at the same thoracotomy. We did not find any mention of this approach in the literature available to us.
Two pediatric oncology patients with Ewing's sarcoma and one with mixed germ cell tumor were treated with drug regimens that included bleomycin or cyclophosphamide. Despite progress to apparently complete remission, all manifested pulmonary nodules on computed tomography during or at the end of treatment. Thoracoscopic biopsy to confirm metastasis revealed instead fibrotic lesions apparently attributable to bleomycin or cyclophosphamide. After cessation of chemotherapy, the pulmonary lesions resolved and all three patients sustained their remissions. The case histories and comments on the diagnosis and management of pulmonary nodules are reviewed.