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Biomedical subjects

D Gutman

Publications and source records attributed to D Gutman.

At least 55 records · Page 3Linked to original sources
PubMed1979

Treatment of oral hemangiomas with local sclerosing agents.

Twenty-four cases of hemangiomas of various sizes in the oral cavity and lips were treated with local injections of a sclerosing agent (3% Sotradecol - sodium tetradecyl sulfate). No side effects were noticed and the lesions disappeared without scarring. The article discusses the practical aspects of this therapy.

Adolescent↗
PubMed1979

Local reaction to gingival injections of MER/BCG in guinea pigs.

The local reaction to gingival injections of methanol extraction residue of BCG (MER/BCG) was investigated in guinea pigs to help determine the potential of this agent in treating oral carcinoma. The drug was used in a standard and diluted form. Both concentrations were well tolerated and caused no ulceration or necrosis. Histological examinations performed at predetermined intervals showed an inflammatory response to the standard and the diluted solution. This reaction was more pronounced when the higher concentration was used. No changes in the alveolar bone were found in either of the groups. Complete healing with scar formation was evident four to six weeks later. The absence of severe reactions after injections of MER should encourage further investigations of this agent in the local treatment of neoplastic processes in the oral cavity.

Animals↗
PubMed1978

Sialochemistry of patients with rheumatoid arthritis. Electrolytes, protein, and salivary IgA.

Sialochemistry was undertaken to detect subclinical involvement of salivary glands in patients with rheumatoid arthritis (RA). The concentrations of salivary sodium and IgA were significantly elevated in 24 percent of the RA patients. Eighty per cent of the patients with elevated sodium and IgA concentrations had keratoconjunctivitis sicca as well. No correlation between serum and salivary IgA levels was found. The results indicate that salivary sodium and IgA levels can be used for detection of subclinical salivary gland involvement and for follow-up of RA patients.

Adolescent↗
PubMed1978

Sialochemistry of KCS patients.

Sialochemistry was used to detect salivary gland involvement in KCS patients. Significantly elevated IgA was found in 52% of the patients, potassium in 48% and sodium in 32%. No correlation between the grade of Schirmer's test and the extent of changes in salivary composition was observed. The results indicate that salivary IgA, K and Na concentrations can be used for detection of salivary gland involvement of KCS patients.

Adult↗
PubMed1977

The effect of chlorhexidine mouth rinses on oral Candida in a group of leukemic patients.

Eighteen leukemic patients were examined for the presence of Candida albicans in the oral cavity. Fifteen patients were found to be Candida "carriers." Nine of the patients were put on a chlorhexidine mouth rinse regimen. Although chlorhexidine was clearly fungicidal in vitro, no decrease in Candida titer was obtained with the mouth rinse. The ineffectiveness of the drug in vivo might be due to the specific location of Candida organisms in the oral mucosa.

Biguanides↗
PubMed1977

A strip test for detecting Candida in the oral cavity.

One-hundred and twenty persons were screened for the presence of Candida in the mouth. Salivary samples were cultured on Sabouraud's agar, on yeast extract, and on Microstix. Microstix is a new and simple method testing for Candida. The reliability of the strip for detecting clinically identified candidiasis in severely ill patients was 100 per cent. Of ninety-three clinically healthy controls, forty-five were found to be Candida carriers according to the two conventional methods (Sabouraud's agar and yeast extract), but only forty-one of them by the strip. The discrepancy might be explained by the limit of the sensitivity of the strip (5.10(2) yeast per milliliter). The strip is recommended for testing clinically suspected candidiasis and is very useful for screening.

Candida albicans↗
PubMed1977

Acute maxillary sinusitis caused by a guttapercha point.

A case of acute sinusitis caused by a gutta-percha point is presented. The foreign body was introduced into the sinus during root therapy. Antibiotic therapy was ineffective. Surgical treatment consisted of radical antrostomy and removal of the foreign body.

Adult↗
PubMed1976

Salivary IgA and serum IgG and IgA in recurrent aphthous stomatitis.

Salivary flow rate and sIgA were measured in twenty-one patients suffering from recurrent aphthous stomatitis (RAS). Out of this group ten volunteered for continuous study. In these patients salivary IgA and serum IgA and IgG were measured every 3 days for 3 weeks. All parameters were in the physiologic range of healthy people. No correlation with the clinical condition of the patients was found.

Adolescent↗