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Biomedical subjects

D Hürzeler

Publications and source records attributed to D Hürzeler.

7 recordsLinked to original sources
PubMed1979

[Cryoapplication in the field of ORL (author's transl)].

After drawing attention to the literature concerning the use of cryotherapy in the field of ORL, the results of this therapy based on 40 cases, involving a total of 73 applications, are set out. Of mucous membrane affections otherwise resistant to therapy and inclined to recidivation, it was possible to cure two thirds of the cases and achieved an improvement in five further cases, giving altogether more than three quarters of the cases showing favourable results. An appliance was used which achieved a temperature of -40 degrees C at the tip of the probe, using the Joule-Thomson principle with expansion of nitrous oxide. This temperature is sufficiently low to effect surface changes, but is not so low as to cause destruction of larger amounts of tissue. Cryotherapy should occupy a permanent place in medical practice.

Cryosurgery↗
PubMed1979

[Bronchoscopy with a rigid tube, an obsolete method?].

Of the two methods of bronchoscopy, the rigid bronchoscope and the flexible instrument, it is clear that one cannot be used to the complete exclusion of the other. Both methods have their advantages and disadvantages. The rigid tube has many diagnostic and especially therapeutic advantages in the main bronchi, while the flexible instrument displays its strong points in the peripheral areas. The two methods complement one another. Bronchofiberscopy alone cannot be recommended, but if it is carried out nevertheless it is merely a general bronchoscopy and the limitations must be taken into consideration. It must be possible to deal with any complications which may arise.

Anesthesia, Local↗
PubMed1978

[UV-fluorescence-bronchoscopy].

In UV fluorescence bronchoscopy the patient inhales 5 ml of a 5% aqueous solution of fluorescein by compressed air spray, together with a beta2-stimulator, 10-15 min before the bronchoscopy. After the dyestuff which has collected in the secretion has been coughed up or drawn off, only carcinomata, nonciliated metaplastic forms of the mucous membrane, macroscopically non-visible tumour infiltrations into the mucous membrane, and lymphangiosis carcinomatosa remain stained. Under UV illumination, these areas can be visualized for location of points to be examined by biopsy. Interested readers are called upon to form themselves into a study group.

Bronchial Diseases↗
PubMed1975

Blue light endoscopy.

The introduction of high intensity proximal light sources has greatly improved the already high standard in technique of endoscopy. The enable us to illuminate the periphery of the bronchi. The advantage of better illumination must, nevertheless, be paid for with a levelling of contrast, as the bright light outshines the fine differences (e.g., tubercles in yhr mucous membrane). In order to heighten the contrast, first theoretical, then practical tests were carried out with different colored lights. Filters (red, green, yellow and light blue) were placed in front of the light source and the subjective perceptible changes in contrast examined. These tests showed that the light blue filter gave a heightened contrast between light and dark red as well as between yellow and red. Intra- and submucosal nodules, scars, metaplasias, hyper- and parakeratoses as well as precancerous conditions are more clearly visible in the mucous membrane. Circumscribed lesions are better seen and specimens for histological vertification are more accurately located for biopsy. Foreign bodies are more easily grasped. The remaining filters heighten the contrast in special cases (such as mycosis and colored foreign bodies). Individual filters or multifilter disc placed between the light source and the glass fiber light carrier are easy to manipulate, so that colored light can be employed in routine bronchoscopy in order to improve diagnosis.

Bronchoscopes↗
PubMedDate not supplied

Ultraviolet-fluorescence bronchoscopy in early detection of bronchogenic carcinoma.

The still unsatisfactory prognosis of bronchogenic carcinoma prompted the search for possibilities of better early and detailed diagnosis. This led us to the idea of UV-fluorescence bronchoscopy. The patient inhales 5 ml of an aqueous 5% solution of fluorescein, together with a beta2 stimulator, 10-15 minutes before the bronchoscopy, by means of a pressure inhaler. While the normal mucous membrane cleanses itself by virtue of ciliary action (secretions containing fluorescein are expectorated or drawn off during the bronchoscopy), carcinoma, carcinomatous lymphangiosis, superficial tumor infiltrations and nonciliated metaplasias are stained. These places fluoresce in UV light, even when they cannot be observed with the naked eye or with an optical system. In this way, they are made visible for directed biospy. Malignant changes not discernible by means of the methods hitherto employed can thus be diagnosed and sites determined with greater accuracy for proposed resection.

Bronchi↗