Evaluation of the urinary tract in the neonatal period.
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Biomedical subjects
Publications and source records attributed to D L Gilday.
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The advent of 99mTechnetium phosphate bone scanning radiopharmaceuticals has opened new methods of investigation of pediatric bone diseases. In axial skeleton pain, suspected osteomyelitis, evaluation of vascular integrity and suspected but undetected fractures, the bone scan has proved to be a highly complementary study to the radiologic examination.
Brain scans were performed on 40 patients who had had craniotomies for nonmalignant disease during the preceding 11 years. A significant decrease in radioactivity at the craniotomy site with time was found, and in nine patients studied five years post craniotomy there was no activity at all. Because of the frequent difficulty in interpreting the postcraniotomy brain scan when searching for recurrent tumours, it is recommended that baseline scans be obtained a few months after the operation to allow comparison of increased radioactivity at the craniotomy site with what may be seen on future brain scans.
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Accurate reproducible measurements of the rate of gastric emptying have only been possible since the advent of external radionuclide detection techniques. Indium-113m and a 10-crystal rectilinear scanner have been employed to measure stomach emptying rates. The technique is simple, the results reproducible and it has proved ideal for assessing the results of drug therapy in patients with gastric retention. In the normal individual the T50% was 42 to 95 minutes, and the relationship between counts and time was, to first approximation, a linear function.
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Of 200 patients with seizures who had brain scans, the studies were abnormal in 86% of patients with tumours and in 67% of those with strokes. The scan detected 84% of the 19 potentially curable lesions. There were no false positive studies. Seventy-nine per cent of patients with seizures of less than one year's duration had an abnormal scan; however, the scan was also abnormal in 22% of patients with non-focal seizures of less than one year's duration.
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