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Biomedical subjects

D L Gilday

Publications and source records attributed to D L Gilday.

101 records · Page 6Linked to original sources
PubMed1970

Diagnosis of pulmonary embolism. A correlative study of the clinical, scan, and angiographic findings.

Seventy-one patients with suspected pulmonary embolism had both pulmonary scans and angiograms. Clinically it was impossible to predict the absence or presence of subsequent angiographic evidence of pulmonary embolism in the individual patient. In 24 patients the scans showed defects that were believed to indicate a high probability of pulmonary embolism-namely, perfusion defects that corresponded to specific anatomical segments of the lung together with normal chest radiographs or radiographs suggestive of pulmonary embolism. Specific angiographic evidence of pulmonary embolism was found in 18 (75%) of these patients. Diffuse, patchy, and non-segmental perfusion defects were seen in 28 patients. Only seven (25%) of this group had angiographic abnormalities specific for embolism. In 12 patients with normal lung scans none showed subsequent evidence of embolism by angiography. It is concluded firstly that lung scanning is a sensitive screening procedure for pulmonary embolism and, secondly, that segmental perfusion defects are highly suggestive of pulmonary embolism.

Angiography↗
PubMedDate not supplied

Qualitative phase analysis in pediatric nuclear cardiology: isolation of cardiac chambers and identification of asynchronous contraction patterns.

Qualitative phase analysis of radionuclide angiocardiograms has been applied in pediatric nuclear cardiology. The technique involves the static and dynamic display of phase images. Qualitative phase analysis is valuable in two major images: (a) delineating borders of adjacent cardiac chambers such as the AV valve planes and the borders of the right ventricular outflow tract, for accurate selection of regions of interest, and (b) identifying and evaluating patterns of asynchronous contraction. Radionuclide angiography with phase analysis is a safe, noninvasive, and easily repeatable assessment of cardiac function well suited to patients with congenital heart disease.

Adolescent↗
PubMedDate not supplied

Comparison of SPECT, EEG, CT, MRI, and pathology in partial epilepsy.

Twenty children with partial epilepsy who had surgery between the ages of 4 1/2 months and 18 years were studied preoperatively with electroencephalography (EEG), computed tomography (CT), and technetium-99m hexamethylpropyleneamineoxime 99mTc-HmPAO single photon emission computed tomography (SPECT; 20 interictal, 4 postictal). Fourteen had magnetic resonance imaging (MRI). All had an epileptiform focus (12 unilateral, 8 predominantly unilateral) on EEG. The combination of interictal and postictal regional cerebral blood flow (rCBF) abnormalities alone correlated with EEG foci in 16 of 20 patients. Interictal rCBF abnormalities correlated with EEG foci in 14 of 20. CT findings correlated with EEG foci in 14 of 20. MRI findings correlated with EEG foci in 13 of 14. Pathology demonstrated tumor in 6, cortical dysplasia in 4, mesial temporal sclerosis in 3, Sturge-Weber in 2, cavernous hemangioma in 1, Rasmussen encephalitis in 1, porencephalic cyst and gliosis in 1, and cysts found at surgery (but normal histology) in 2. Interictal and postictal SPECT, EEG foci, and CT findings each correlated with the pathology site in 17, 19, and 15 patients, respectively. MRI correlated with pathology site in 13 of 14 patients. Postictal and interictal abnormalities of rCBF correlated with EEG and pathology as frequently as CT. In 5 patients with normal CT scans and in 1 with a normal MRI, postictal and interictal rCBF correlated with EEG and pathology results; however, these 6 patients all had abnormalities on CT or MRI. SPECT, therefore, may be considered a valuable additional diagnostic procedure in the evaluation of epilepsy surgery candidates in that it adds to the evidence of abnormality at the involved site.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗