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Biomedical subjects

D López Aguado

Publications and source records attributed to D López Aguado.

At least 19 recordsLinked to original sources

[Hypoglossal facial anastomosis as a solution to a total peripheral facial palsy. Our experience].

Hypoglossal-facial anastomosis was performed in four patients with total peripheral facial palsy after removal of cerebellopontine tumors (three patients with neurinoma) and pontine aneurysm (one patient). The anastomosis was performed after a period of 3 months to one year from surgery. The results obtained, concerning the facial activity, were clinically valued according to the tests used (questionnary, and the House-Brackmann paralysis index); the EnOG was used for its electrophysiological assessment. The follow-up period was 4 years with a good facial recovery in three patients and poor in one (class V, 27% in ENoG). We observe that the improvement in function greatly depends on the early surgical process performance.

Adult↗

[Lateral sinus thrombosis due to cholesteatoma. Report of a case and literature review].

After introduction of antibiotics, endocranial complications in otitis media are less common. Lateral sinus thrombophlebitis (LST) incidence has markedly decreased but mortality is still high. This complication should be considered in patients with ear discharge, fever and neurological symptoms. CT-scan and MRI enables early diagnosis and have a role in detecting addition intracranial complications. Surgical intervention should be aggressive and anticoagulation should be considered. We present a case of a woman with othorrea, fever and neurological symptoms. The CT-scan shows us a cholesteatoma that grows intracranial and a LST as complication of it.

Cerebral Angiography↗

[Aural polyp in chronic inflammatory middle ear disease].

240 patients with chronic otitis media (COM) were studied: 166 ears termed as non cholesteatomatous otitis media and 74 with cholesteatoma. In 38 ears an aural polyp was found with no evidence of cholesteatoma in 19 ears (11.4%) whereas a cholesteatoma was present in the remaining 19 ears. The histology of the polyp and the characteristics of the chronic process were matched: a) The aural polyp is an infrequent complication in COM. b) After histological analysis was found to present two different pictures: The inflammatory reaction polyp, present in non cholesteatomatous COM; and the polyp with granulation tissue and foreign body reaction (keratina) usually found in cholesteatomatous COM. c) The finding of granulation tissue reaction and keratina in an aural polyp is a good predictor for the presence of a cholesteatoma.

Cholesteatoma, Middle Ear↗

[Correlation between otoacoustic emissions and BAEP. The importance of their combined use].

Auditory Brainstem Response (ABR) of 50 newborn with negative transient evoked acoustic emissions (OEAT) was performed. 54% of them had no family history of sensorineural hearing loss (SHNL) and no risk factors were found. In 70% of cases ABR recording was negative. Follow up did show that 60% of them had normal recordings of hearing and in a 40% different stages of hearing loss were seen. To establish a definitive diagnosis a 1 to 9 month period is necessary.

Deafness↗

[Evaluation of electroneurography as a prognostic method in the development of peripheral facial paralysis].

Electroneurography (EnoG) is a prognostic test used in the assessment of the peripheral facial nerve paralysis. We believe that when performed in standard conditions and together with the clinical evolutive parameters, it is very useful to reveal the critical time for a more radical treatment. We studied 44 patients; 13 patients had greater than 90% neural degeneration on EnoG. 5 of them underwent facial nerve surgical decompression due to a poor clinical outcome and up to three of these patients had a normal facial function after this.

Adolescent↗

[Forestier's syndrome. Report of two cases].

Diffuse idiopathic skeletal hyperostosis (DISH) with cervical involvement which cause dysphagia is a rare disease. The otolaryngologist usually can make its diagnostic with a barium swallowing esophagogram. Two patients with DISH are reported.

Aged↗

Influence of human wet cerumen on the growth of common and pathogenic bacteria of the ear.

The available data on the effect of human wet cerumen on bacterial growth are not conclusive. Nevertheless it is widely accepted that cerumen has a bactericidal effect. In this study the activity of human wet cerumen on bacterial growth was assessed by applying cerumen suspensions to bacterial cultures. Bacterial counts were performed before and after application of cerumen suspensions. A total of 383 assays was carried out with 73 pools of cerumen that were tested against cultures of Staphylococcus aureus, Staphylococcus epidermidis, Corynebacterium spp., Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa and Serratia marcescens. An increase in growth occurred much more frequently than a decrease in growth in almost every microrganism tested, with the mean increase percentage being much higher than the mean decrease percentage, except in the case of S. aureus. The largest average growth increase was obtained with E. coli. The largest average decrease in bacterial growth was recorded with S. marcescens. Our study does not support the conception of a decrease in bacterial growth produced by humen wet cerumen. In vitro, the most observable effect was in fact an increase in microbial growth.

Adolescent↗

[Lymphoepithelial carcinoma of the larynx. Report of 2 cases].

Laryngeal lymphoepithelioma is a rare tumor (16 cases in the literature). It is an association of undifferentiated, non-keratinizing cells and normal lymphocytes and plasma cells. The Epstein-Barr virus is rarely found. To determine the actual nature of the tumor, a complete histochemical workup and/or electron microscopy often are needed. Cervical lymph node involvement is common. We report the cases of two men. In one patient, the tumor was located in the glossoepiglottic fold and in the other it was located in the left ventricule and false vocal cord. EB virus was absent in both cases. Cervical lymph node metastases were found, but not distant metastases. One patient was treated by irradiation and the second underwent surgery (supraglottic laryngectomy and cervical dissection) and was referred to radiotherapy for further treatment.

Aged↗

Study of common aerobic flora of human cerumen.

Cerumen is the product of the secretion of the sebaceous, ceruminous or apocrine glands together with cells exfoliated from the cornified stratum of the epithelium of the external auditory canal (EAC). In the present study we identified and quantified common flora of human cerumen. The mean count obtained was 10(6) microorganisms per ml of cerumen suspension. In 24 pools of cerumen (33.3 per cent) the isolates were monomicrobial, Staphylococcus epidermidis (12), Corynebacterium spp (10), Staphylococcus aureus (1) and Streptococcus saprophyticum (1). In 48 pools (66.6 per cent) we found polymicrobial isolates. The most commonly isolated bacteria in these polymicrobial isolates were S. epidermidis (35) and Corynebacterium spp. (43). It is noteworthy that there were isolates of Candida albicans in three cases; in one case of Pseudomonas stutzeri, in one case of Pseudomonas aeruginosa, and, on seven occasions, of S. aureus. The organisms isolated as common bacterial components of human cerumen in our experience were similar to those found by other authors. However, the mean count was much higher. This could be related to climatic conditions and to the length of time the cerumen had remained in the external auditory canal.

Adolescent↗

[Relation between the Toynbee phenomenon and tube dysfunction].

The effect of the Toynbee phenomenon in patients with nasal packing was studied. Nasal packing was used in 35 patients admitted for surgical correction of septal deviation. Middle ear pressure was measured during nasal packing and the results were compared with nasopharyngeal pressure gradients recorded during the Toynbee maneuver. The aim of the study was to demonstrate that one of the main causes of tube dysfunction during nasal obstruction is the Toynbee phenomenon.

Eustachian Tube↗

[The Toynbee's phenomenon effect on the middle ear during nasal tamponade].

Is has been demonstrated by some AA. that nasal packing can cause Eustachian tube dysfunction. There are several motives, isolated or united as well, that have been offered to account for Eustachian tube dysfunction, but the exact causative mechanism still remains unclear. We have studied the Eustachian tube function in 75 patients with septal deviation that underwent septal surgery followed by anterior nasal packing. The aim of our work is to demonstrate that one of the main causes of the tubal dysfunction, after bilateral packing of nasal cavities, is the Toynbee's phenomenon.

Adolescent↗

Histological structure of the vocal fold in the human larynx.

Histological analysis of the human vocal folds, focused particularly on the lamina propria of the vocal muscle of fetuses, infants, and adults in horizontal laryngeal sections, allowed us to show the differences in morphology and composition according to the laryngeal development. Our results indicate that the origin of the vocal fold is independent of the origin of the other portions of the larynx, and the influence of the zone known as macula flava in the maturation of the vocal fold is an age-related process.

Adult↗

[DNA papillomavirus detection in head and neck benign proliferative lesions].

In a retrospective study, human papillomavirus (HPV) (6/11, 16 and 18 types) were tested using polymerase chain reaction (PCR), in stored formalin-fixed, paraffin-embedded tissue sections, from 36 head and neck adult papillomata. The results, only 20 percent of positive cases, are non consistent with the role of the HPV infection in the etiology of head and neck papillomata in adult patients. However we detect HPV-18 positivity in papillomata with dysplasia.

Adult↗

[The phylogenic imprinting on the morphogenesis of the middle and external ear].

The AA. present a review of the embryologic development of both external and middle ear and its relationship with the phylogenesis. They consider the trascendence of this linkage in the shaping and in the physiology of the conductive apparatus of the sound and even admit the possibility of determine diseases like the cholesteatoma.

Ear, External↗

[The phylogenetic imprint on the embryonic development of the inner ear].

The AA. present a review of the embryologic development of the internal ear linked with evolutive phylogenic events, which will determine the morphogenesis of this organ, of ancestral origin. The significance of those phenomena in order to bring about several physiological attributes as the possibility of vestibular hearing and even to set off pathologic conditions like the otosclerosis are considered.

Cochlea↗

[Influence of climate factors on the course of secretory otitis media].

For many years there has been admitted a close link between climatology and the course of secretory otitis media. Despite of that there are few articles in medical literature covering this subject. As a consequence of the special climate of their Island the AA. study the evolutive run of the illness under different rates of humidity.

Acoustic Impedance Tests↗

[Morphometric study of the intrapetrous passage of the facial nerve in adult temporal bones and its application to the study of the pathogenesis of Bell facial paralysis].

After a morphometric study, done in adult temporals, of the inner diametre of the fallopian bony canal, of the thickness of both the epineural space and the nerve trunck (in petrous, tympanic and mastoid segments) and the like with the geniculate ganglion and the pyramidal bend, the AA. thrown out the conclusion that when a generalized edema of the nerve is expected the labyrinthine segment or the distal portion of the mastoidal segment are the sites to be found most precocious or heaviest compressed.

Adult↗

[The etiology of secretory otitis media].

In this paper we pretend to study the incidence of the OMS according to age and sex, as the possible paper played by the hypertrophy of the pharyngeal tonsil and the allergy of its production. We observe a mayor presentation between four and six years old, no difference occurs in relation to sex, and on important paper of the hypertrophy of the pharyngeal tonsil in the etiology of the OMS superior to the roll played by the allergy.

Acoustic Impedance Tests↗