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Biomedical subjects

D M Barber

Publications and source records attributed to D M Barber.

24 records · Page 2Linked to original sources
PubMed1975

Biochemical studies of the "collapse syndrome" in suckled calves.

A total of 351 single-suckled beef calves were blood sampled at twice-weekly intervals for the first two and a half weeks of life. Twenty three of them died, 13 of a syndrome characterised by acute collapse and 10 of diarrhoea which had persisted for several days before death. Those which died acutely showed a sudden terminal rise in blood levels of potassium, magnesium, inorganic phosphate and total protein. Those which died after several days of diarrhoea showed a more gradual increase in blood chloride and urea concentrations and in packed cell volume values. It is suggested that these changes indicate a difference in the pathogenesis of the two situations. Calves which died had lower blood glucose levels before the onset of clinical signs than those which survived. It is suggested that this may have been a contributory factor in their mortality.

Animals↗
PubMed1975

Immune globulin studies of the "collapse syndrome" in suckled calves.

A total of 351 single suckled beef calves were blood sampled during the first three days of life and thereafter twice weekly until five samples had been obtained. Eighty four calves suffered from diarrhoea and 23 of these died. No relationship could be found between the total circulating immune globulin level of a calf and its subsequent fate, suggesting that the syndrome with which many calves were affected is different in character from other forms of neonatal bovine diarrhoea.

Animals↗
PubMed1975

Bacteriological and pathological studies of the "collapse syndrome" in suckled calves.

During the winter of 1971-72 faecal samples from 91 diarrhoeic calves, 25 of which were considered to be suffering from the "collapse syndrome" were examined bacteriologically. E coli of serotypes reported as having the ability to produce enterotoxins were isolated from most of the calves with the "collapse syndrome", but from only a few of the other diarrhoeic calves, as well as a few unaffected in-contact animals. On post mortem examination, abomasal dilatation was a characteristic finding in calves dying of the "collapse syndrome" but not of other diarrhoeic deaths. The significance of these findings is discussed.

Abomasum↗
PubMed1975

The epidemiology of the "collapse syndrome" in suckled calves.

Cases of a diarrhoeic syndrome characterised by acute collapse were seen in single-suckled beef calves on hill farms during a three year period. The association between the occurrence of this syndrome, which we have termed the "collapse syndrome", and various epidemiological parameters, is investigated and discussed.

Animal Feed↗
PubMedDate not supplied

Antibiotic persistence and tolerance in the lactating sheep following a course of intramammary therapy.

The commercial use of sheep for the production of milk and milk products is attractive to farmers actively diversifying their dairy interests due to the impact of the quota system. As intensification of milking increases, flock sizes will enlarge and the incidence of ovine mastitis will inevitably increase. The pharmaceutical industry and the veterinary practitioner will be required to provide advice and data upon the performance of currently available bovine intramammary preparations for the sheep. This study produces evidence to confirm that one available bovine intramammary preparation, when infused into milking sheep, produced a withholding time approximately three times as long as that defined for the cow. Following a course of three infusions over a period of 24 hours after consecutive milkings, milk was not acceptable for human consumption or for the production of cheese and yoghurts until 136 hours following the final infusion. This situation is likely to be representative of that which will occur with other intramammary products used in the ovine species following infusion with bovine intramammary preparations.

Amoxicillin↗