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Biomedical subjects

D O Trainer

Publications and source records attributed to D O Trainer.

At least 37 records · Page 2Linked to original sources
PubMed1972

Influenza in Canada geese.

The role of wild avian species in the natural history of influenza is unknown. A serological study was carried out to ascertain the prevalence, distribution, and types of influenza antibody in several wild Canada goose populations. Geese were trapped and blood samples were obtained in each of 4 consecutive years, 1966-69. Antibody to influenzavirus was found in 66 (4.7%) of the 1 401 Canada geese tested by the haemagglutination inhibition (HI) test. Antiribonucleoprotein antibody was found in 8 of 1 359 sera tested by the agar gel precipitation (AGP) test. An increase in the percentage of reactors was seen each year. This increase was greater in two refuges with nonmigratory flocks. HI antibody was found against the turkey/Wisconsin/66, turkey/Wisconsin/68, turkey/Canada/63, and turkey/Alberta/6962/66, or closely related viruses. No antibody was found against duck/Ukraine/1/63 or human A/Hong Kong/68 virus at a time when the latter was prevalent in human populations, suggesting that Canada geese played no direct role in spreading the virus.Canada geese were experimentally exposed to turkey/Wisconsin/66 and turkey/Wisconsin/68 viruses; mallard ducks were exposed to turkey/Wisconsin/66 virus. HI antibody developed in 75% of the geese and 40% of the ducks but was generally short-lived. Anti-RNP antibody was detected in 15% of the exposed geese but in none of the ducks. Virus was recovered from 3 of 10 adult ducks but not from geese. None of the birds showed signs of disease.

Animals↗
PubMed1971

Bluetongue virus: some relationships among North American isolates and further comparisons with EHD virus.

Seven isolates of bluetongue virus with different isolation histories and one isolate of the virus of epizootic hemorrhagic disease of deer were cloned by three consecutive plaquings in L-929 cells. The isolates were categorized on plaque size and margin. Antisera to the bluetongue virus isolates were produced in calves and antiserum to epizootic hemorrhagic disease virus in deer. Plaque reduction neutralization tests were done using the eight isolates and antisera to six of these. The isolates could be partially categorized on plaque type. In the plaque reduction neutralization test, all of the bluetongue viruses cross reacted and although differences were frequently observed, no obvious antigenic classification was possible. Reactions between the bluetongue viruses and epizootic hemorrhagic disease virus were all within the limits of what is presently considered to be non-specific inhibition.

Animals↗
PubMed1970

Polychlorinated biphenyl: interaction with duck hepatitis virus.

Ten-day-old mallard ducklings fed a polychlorinated biphenyl at concentrations of 25, 50, and 100 parts per million for 10 days suffered no apparent clinical intoxication. Five days later these birds were challenged with duck hepatitis virus, and they suffered significantly higher mortality than birds which were not exposed to the polychlorinated biphenyl.

Animals↗
PubMed1970

Experimental haemonchosis in white-tailed deer.

White-tailed deer (Odocoileus virginianus) were successfully infected with Haemonchus contortus of sheep origin. Individual deer in each of three groups were inoculated with 0, 25,000, and 100,000 larvae respectively. Severity of infection was related to dose and signs of infection were most obvious in the heavily inoculated animals. Infected deer were weak, emaciated, and anemic, similar to the clinical response in sheep. Hemoglobin, packed cell volume, and total serum protein values for both infected groups were significantly lower than for the controls. Inhibition of larval growth was noted in both infected groups, but was most pronounced in the group which received 100,000 larvae. Inhibition of egg production was also noted in this group. The potential importance of H. cortortus in deer populations was discussed.

Animals↗
PubMed1970

Bluetongue virus: (1) in pregnant white-tailed deer (2) a plaque reduction neutralization test.

Six white-tailed deer (Odocoileus virginianus) were infected with bluetongue virus (BTs, vaccinal strain) approximately one-third of the way through their gestation period. One deer died of bluetongue 21 days after inoculation. Of the five surviving the infection, one had two mummified fetuses, and the others no fetuses upon euthanasia two weeks after term. Fetuses were present in two control deer and in the one which died of bluetongue. A plaque reduction neutralization test for bluetongue virus was developed and described for the first time and its sensitivity illustrated by high post inoculation titers which ranged from 1:3200 to greater than 1:16000.

Abortion, Veterinary↗