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Biomedical subjects

D O Trainer

Publications and source records attributed to D O Trainer.

At least 55 records · Page 3Linked to original sources

The use of wildlife to monitor zoonoses.

Wildlife are usually considered vectors, reservoirs or primary targets of infectious disease. A seldom considered epidemiological role which they can play involves their use as disease sentinels for the detection and monitoring of zoonoses. Their potential for such utilization has been demonstrated with the wild turkey (Meleagris gallopava intermedia) and St. Louis encephalitis in Texas and the white-tailed deer (Odocoileus virginianus) and California encephalitis in North America. The limitations and criteria which are important in the use of wild populations for "sentinel" duty are discussed.

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Serologic evidence of bunyamwera group arbovirus infections in Wisconsin and texas deer.

Sera of 81 white-tailed deer from south Texas and 283 white-tailed deer from Wisconsin were tested for neutralizing and hemagglutination-inhibiting antibodies to arboviruses of the Bunyamwera group. Neutralizing antibodies were detected in 100% of the Texas deer sera and hemagglutination-inhibiting antibodies were detected in 61% of those sera collected in 1969 and 78% of those sera collected in 1963. The prevalence of both neutralizing and hemagglutination-inhibiting antibodies in Wisconsin deer sera varied from 72-100% and 42-79% respectively depending on the geographic area tested in the years 1963 and 1969.

Animals↗

Isolation of a bunyamwera group arbovirus from a naturally infected caribou.

A Bunyamwera group arbovirus was isolated from the blood and from the brain of a female caribou parasitized with meningeal worms. The virus passed through a 0.45 micron filter; was ether sensitive; possessed no hemagglutination properties; could be propagated in suckling mice, 6-day old chick embryos, and BHK-21 tissue culture; and produced plaques in chick embryo fibroblast tissue culture. Neither complement-fixation or neutralization tests were sensitive enough to determine the serotype of the virus.

Animals↗

Experimental bluetongue disease in white-tailed deer.

Nine white-tailed deer and six sheep were experimentally exposed to the California BTV-8 strain of bluetongue virus. The infections were fatal for seven of the nine deer. An additional deer died from exposure to an isolate of bluetongue virus from bighorn sheep. Clinical signs and lesions of bluetongue in deer were described. The incubation period, signs and lesions of bluetongue and epizootic hemorrhagic disease of deer appear to be similar. Virus isolations were made from the blood and a variety of tissues of exposed deer and identified as bluetongue virus. Neutralizing antibodies were detected in all of the convalescent sera.

Animals↗