[Usefulness of laparotomy in the differential diagnosis of hepatic cystic degeneration diagnosed as hepatic echinococcosis].
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Biomedical subjects
Publications and source records attributed to D Prokopowicz.
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In 84 rabbits, fibrinogen behaviour and fibrinolytic activity of the plasma euglobulins were evaluated in the course of experimental salmonellosis caused by S. typhimurium, S. choleraesuis, and S. agona. 10 healthy animals with pseudoinfection served as controls. Disturbances of hemostasis expressed by a use of the fibrinogen level and inhibition of plasma-euglobulin fibrinolysis were established. An analysis of these changes and evaluation of the lethality among the animals used in the experiment revealed that the course of the disease is depending, inter alia, upon the type of Salmonella involved.
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The authors have analysed the influence of experimental infection of rabbits with Salmonella agona on lysozyme activity in the blood serum of examined animals. 37 rabbits were used in the experiments; experimental salmonellosis was developed in 22 out of this number, the remaining ones (15 rabbits) served as controls A statistically significant increase of lysozyme activity has been found in the serum of sick animals in the acute stage of the disease. A significantly high activity of this enzyme was observed in the diluted blood serum of experimental animals. No correlation was founds between the number of leucocytes and the percentage of granulocytes, and the lysozyme activity.
Organ changes evoked by infection with Salmonella agona were evaluated in 30 rabbits. Pathological changes were found not only in the intestines but also in the liver, lungs, spleen, kidney and suprarenal glands. The changes were different from those induced by other serotypes of Salmonella.
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