Biomedical subjects
D R Ginn
Publications and source records attributed to D R Ginn.
Guillain-Barré syndrome. An uncommon but severe illness.
It is important for primary care physicians to be familiar with Guillain-Barré syndrome, a relatively rare disorder that may occur after another illness or after stress such as surgery. Although most patients recover fully, respiratory failure and cardiovascular failure are possible complications. Rapid diagnosis and referral to specialists experienced in plasmapheresis therapy can significantly benefit patients.
Parathyroid adenoma manifested as pancreatitis and polyuria.
Although the data used to explain a relationship between hyperparathyroidism and pancreatitis remain incomplete, there does appear to be a relationship between the two. We believe our patient's clinical course strongly supports this.
Respiratory infections in ambulatory adults. Choosing the best treatment.
The diagnosis and treatment of respiratory tract infections in ambulatory adults is challenging. The prevalence of these conditions outstrips the medical profession's efficiency and effectiveness in dealing with them. However, selecting diagnostic techniques that identify causative organisms and therapeutic agents targeted to those organisms should lead to a reduction in the morbidity and mortality associated with these illnesses.
Outpatient conversion of treatment to potassium-sparing diuretics.
Thiazide diuretics frequently cause a decrease in serum potassium levels. In this study, 34 percent of patients taking hydrochlorothiazide had serum potassium levels below 3.5 meq/liter. The response of the serum potassium level was studied after treatment in 56 patients was switched from 50 mg of hydrochlorothiazide daily to either two capsules of hydrochlorothiazide/triampterene (Dyazide), or one tablet of hydrochlorothiazide/amiloride (Moduretic) daily, over nine to 15 months. The 24 patients whose treatment was changed to Dyazide had a rise in serum potassium levels from a mean of 3.56 meq/liter to 4.17 meq/liter in two to three weeks. The 32 patients whose treatment was changed to Moduretic had a rise in serum potassium levels from a mean of 3.76 meq/liter to 4.14 meq/liter in two to three weeks. The resultant rise in potassium levels was stable throughout the follow-up period in both groups. Patient acceptance of this change was excellent.
Excessive phenylpropanolamine ingestion followed by subarachnoid hemorrhage.
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