On estimating parameters of the binomial model for transmitter release at synapses.
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Biomedical subjects
Publications and source records attributed to D Schenzle.
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The age-specific prevalence of hepatitis A antibodies has been analyzed using a catalytic epidemic model for populations in seven European countries: West Germany, Norway, Greece, Switzerland, Holland, France and Sweden. The results indicate a significant decline in the force of infection in recent decades. However, there are substantial differences between the countries, especially between the Scandinavian countries and Greece. The incidence of hepatitis A in Norway and Sweden has declined since 1930, while a downward trend in incidence in Greece may have started only recently.
The hypothesis of a decline in the incidence of hepatitis A infections in Germany in recent decades was confirmed by determining the prevalence of hepatitis A antibody (anti-HAV) in sera collected in 1965 and in 1975 under the same conditions in North Germany. The prevalence of anti-HAV correlated with the year of birth and was independent of the time of serum sampling. The force of infection fell from 0.04 in 1945 to 0.005 in 1965 as judged from a catalytic epidemic model with a sigmoidal decrease.
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