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D Tullio

Publications and source records attributed to D Tullio.

30 records · Page 2Linked to original sources
PubMed1981

[Vectorcardiographic study in elderly subjects with a normal ECG (author's transl)].

In order to estimate if the elderly subjects with a normal ECG present vectorcardiographic (VCG) changes, were analyzed the VCG of 35 patients of age between 65 and 84 years with a normal ECG, negative anamnesis, objective cardiovascular examination and no radiological alteration of the cardiac image. These patients were divided in two groups according to the age: the first included 20 patients of age between 65 and 74 years, the second 15 patients between 75 and 84 years. A group of control with an average variable between 40 and 59 years, was also examined. The P, QRS and T loops were examined. The P loop, with a lessened magnitude (mV), particularly in second group, was directed inferiorly and anteriorly as regards controls, with initial, middle and/or terminal slurrings. On the QRS loop, in second group, were found the following changes: the Initial Vectors are directed inferiorly and anteriorly, the Maximum Spatial Vector more superiorly and anteriorly and Terminal Vectors more superiorly and posteriorly therefore the loop appeared frequently distorted on the frontal plane. The loop, with a lessened magnitude, particularly in second group, more frequently counter-clockwise inscripted on the frontal plane. Time of occurrence of Maximum QRS Vector (msec) was found more precocious. The T loop, with a lessened magnitude, particularly in second group, resulted slightly deviated inferiorly and anteriorly. The observed changes appeared modest and of a kind more quantitative, that is expressed by changes in the magnitude and relation between different vectorial groups, than qualitative, that is in relation to changes in the orientation and succession of such vectors. These changes, more frequent in the second group patients, don't give generally problems of differential diagnosis with the myocardial infarcts, hypertrophies or conduction disturbances. They are likely in relation to histological and/or metabolic changes in the myocardium common tipic of old age and in a lesser degree to anatomic and haemodynamic changes in the senile heart.

Adult↗
PubMedDate not supplied

[Effects of ticlopidine on platelet function at rest and after exercise in patients with previous myocardial infarct. An acute crossover double-blind study].

The effects of Ticlopidine on platelet function at rest and after exercise test in 12 patients with a history of myocardial infarction but no risk factors and/or residual angina, were investigated. The patients were treated with 500 mg per diem Ticlopidine or placebo for 15 days in a crossover double-blind study. Blood samples were taken before and 3 minutes after maximum effort exercise cycle tests. Blood samples from 25 healthy volunteers of comparable age and sex were used for control purposes. The parameters examined were: platelet aggregation induced by ADP (1 and 3 mumol/l), Arachidonic Acid (AA) (1.3 mmol/l) and collagen (2 micrograms/ml); the presence of circulating platelet aggregates and plasmatic fibrinogen levels. When compared with the controls, the patients showed higher levels of aggregation caused by ADP, AA and collagen as well as circulating aggregates. Exercise produced a statistically significant increase in platelet activation, while Ticlopidine significantly inhibited the platelet aggregation induced by ADP, AA and collagen as well as circulating aggregates both at rest and after the exercise test. Fibrinogen levels were higher in the heart attack patients than the controls especially after exercise, but not to a statistically significant degree. Treatment with Ticlopidine did not influence plasma fibrinogen levels. It is not known whether the patients with signs of effort-induced platelet aggregation run a higher risk of ischaemic cardiopathy or whether drug treatment could prevent this eventuality.

Adult↗
PubMedDate not supplied

[Dilated cardiomyopathy in childhood. Description of a surgical case].

The Authors report their experience with a case of idiopathic dilated cardiomyopathy in a 13 years old girl with quick evolving heart failure, not responsive to pharmacologic therapy, heart transplanted. The prognostic evaluation was related to choice of therapy. Histologic examination shows, with the known change, the presence of rich fat infiltration in subepicardic myocardium. It is also possible explain this change as a not specific answer to different pathogenic agents.

Adolescent↗