Comparative aspects of the action of chloramphenicol and thiamphenicol on bacterial ribosomes.
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Anti-Bacterial Agents↗
Biomedical subjects
D Vazquez
Publications and source records attributed to D Vazquez.
Ribosomal activities dependent on elongation factors T and G. Effects of methanol.
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Anti-Bacterial Agents↗
Differences in eukaryotic ribosomes detected by the selective action of an antibiotic.
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Animals↗
The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes.
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Anti-Bacterial Agents↗
Ribosomal sites involved in binding of aminoacyl-tRNA and EF 2. Mode of action of fusidic acid.
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Binding Sites↗
Inhibition by aminoacyl transfer ribonucleic acid of elongation factor G-dependent binding of guanosine nucleotide to ribosomes.
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Binding Sites↗
Antibiotic action in protein synthesis.
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Acyltransferases↗
Preparation of pure (3H)anisomycin by tritium exchange labeling.
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Anti-Bacterial Agents↗
Quantitative binding of 14C-erythromycin a to E. coli ribosomes.
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Carbon Radioisotopes↗
Reconstitution of the 50S ribosome subunit. Role of proteins L 7 and L 12 in the GTPase activities. Site of action of thiostrepton.
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Journal Article↗
Failure of fusidic acid and siomycin to block ribosomes in the pretranslocated state.
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Amino Acids↗
Elongation factor T-dependent hydrolysis of guanosine triphosphate resistant to thiostrepton.
Methanol stimulates the hydrolysis of GTP catalyzed by bacterial ribosomes in the presence of the chain elongation factor T (EF-T). The methanol-stimulated activity is uncoupled from aminoacyl-tRNA binding to the ribosomes and does not require the presence of either synthetic polynucleotide messenger or aminoacyl-tRNA. When these reactants are present, along with EF-T, GTP, and methanol, the ribosomal binding of aminoacyl-tRNA is inhibited by thiostrepton but the uncoupled, EF-T-dependent hydrolysis of GTP is resistant to the antibiotic.
Anti-Bacterial Agents↗
Survey of inhibitors in different steps of protein synthesis by mammalian ribosomes.
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Anti-Bacterial Agents↗
Inhibitors of protein synthesis by ribosomes of the 80-S type.
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Acyltransferases↗
Reconstitution of the 50 S ribosome subunit. Localization of activities related to the peptidyl transferase centre.
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Journal Article↗
Reconstitution of the 50 S ribosome subunit. Localization of G-dependent GTPase activity.
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Journal Article↗
Substrate- and antibiotic-binding sites at the peptidyl-transferase centre of Escherichia coli ribosomes. Studies on the chloramphenicol. lincomycin and erythromycin sites.
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Anti-Bacterial Agents↗
Ribosomes, G-factor and siomycin.
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Anti-Bacterial Agents↗