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Biomedical subjects

D Vuitton

Publications and source records attributed to D Vuitton.

65 records · Page 4Linked to original sources

Intrahepatic lymphoid tissue graft: course of the Gvh reaction induced by Peyer's patches.

To investigate the thymus-dependent immune competence of Peyer's patches, the course of splenomegaly and hepatic perivascular infiltration (PVI) was studied as criteria of graft-versus-host reaction (GvhR). Parental or F1 hybrid lymphoid tissues, were intrahepatically implanted and the ability of Peyer's patches to induce a GvhR was compared to that of spleen, lymph nodes and thymus. A slight but significant delayed increase of spleen index was observed at the 40th post operative day following Peyer's patches implantation whereas the thymus did not induce any modification of this parameter. On the other hand, the PVI was a very early and precise criterion in monitoring the Gvh reaction induced by Peyer's patches, and allowed to postulate that at least one T-cell function is present within the Peyer's patches.

Animals↗

[Campylobacter fetus ssp fetus septicemia associated with a colonic abscess].

Campylobacter is considered to be an opportunistic agent. The authors relate an unusual case with Campylobacter fetus ssp fetus (CF) septicemia and colic abscess. Human Campylobacteriosis is presumed to be a food-born disease related to contaminated animal products such as milk or meat. In some cases CF may be transmitted by drinking water or by fecal soiling via the hands. Conventional treatment uses macrolides with decrease the duration of diarrhea and reduce the fecal excretion of CF. Macrolides are ineffective in CF septicemias. In such cases aminoglycosides seem to be the drug of choice.

Abscess↗

[Relationship between autoimmune diseases and personality traits in women].

The personality traits of 40 women with non organ-specific dysimmune diseases were studied by means of a questionnaire devised to evaluate behavioural components including 48 items divided into 8 different patterns. The patients fell into 3 groups. Group I comprised 20 women with collagen diseases, including systemic lupus erythematosus (n = 8), scleroderma (n = 4), Sharp's syndrome (n = 4), polymyositis (n = 3) and Shulman's syndrome (n = 1). Group II was made of 10 women with either primary (n = 6) or secondary (n = 4) Sjögren's syndrome. Group III consisted of 10 women with vasculitis. Results were compared with those obtained in a control population of 41 women without dysimmune disease. At the time of examination the mean daily dose of prednisone was 10.5 mg. All 40 patients differed from the control group by their unobtrusiveness, self depreciation (P less than 0.01), hyperconformability and excessive kindness (P less than 0.02). Additional traits were a tendency towards contradiction and intolerance in patients with Sjögren's syndrome and a lack of agressiveness combined with a feeling of inferiority in patients with vasculitis. These results confirms that patients with dysimmune disease are psychologically fragile and suggest that the possibility of psychotherapy should be examined in these patients.

Adult↗

Pulmonary embolism from a parasitic cardiac clot secondary to hepatic alveolar echinococcosis.

An exceptional form of hepatic alveolar echinococcosis with metastasis of the right atrium is reported. This cardiac location of the parasitosis was revealed by attacks of pulmonary embolism which produced secondary pulmonary lesions. This case suggests that pulmonary metastases of alveolar echinococcosis of the liver might be due to the migration of parasitic clots from the hepatic veins.

Antigens, Helminth↗

[IgA and its different molecular forms in the mesenteric, portal and peripheral venous blood in man].

The aim of this study was to assess the role of mesenteric blood in polymeric IgA (p-IgA) and IgA2-transport from the intestinal mucosa into plasma and the role of the liver in the clearance of these molecular forms of IgA. The concentrations of IgA, p-IgA and IgA2 were measured in mesenteric, splenic, portal, and hepatic veins of 7 control subjects without liver disease and in portal and peripheral veins of 4 patients with alcoholic cirrhosis. In control subjects, the concentration of the different molecular forms of IgA were not significantly different in mesenteric and in splenic vein. No significant decrease of IgA concentrations was observed in hepatic vein, as compared with portal vein. In cirrhotic patients IgA concentrations were significantly higher than in control subjects, but concentrations of IgA, p-IgA and IgA2 were not different in portal and peripheral blood. These results show that mesenteric vein is not a major way for p-IgA and IgA2 from the gut lamina propria to plasma, and suggest that the origin of a significant part of these molecular forms of IgA could be peripheral lymph-nodes more than gut-associated-lymphoid-tissue. The absence of significant clearance of p-IgA by the liver in normal subjects suggests that abnormalities of hepato-biliary transport of p-IgA is not responsible for the increased IgA levels observed in cirrhotic patients.

Adult↗