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Biomedical subjects

D Whitman

Publications and source records attributed to D Whitman.

6 recordsLinked to original sources
PubMed1998

Activity and passive-avoidance learning in cobalt-injected rats.

A wide range of cognitive-behavioral sequelae, including memory deficits, results from hard metal disease in humans. Cobalt is a common component in the manufacture of hard metals and is a biologically active, toxic substance. This study examined the effects of cobalt exposure in rats. Results showed decreased exploratory behavior and a trend for higher-dose subjects to show decreased passive avoidance learning. No significant differences in active maze learning were found. These results indicate the value of further explorations of the cognitive-behavioral effects of cobalt exposure and suggest a number of methodological cautions.

Animals↗
PubMed1993

MMPI-2 schizophrenia spectrum profiles among schizotypal college students and college students who seek psychological treatment.

The MMPI-2 schizophrenia spectrum profiles of 25 college students with extreme scores on the Perceptual Aberration and Magical Ideation Scales were compared to those of 27 students who requested psychological treatment at a university psychology clinic. Moldin, Gottesman, and Erlenmeyer-Kimling's 1987 classification strategy for schizophrenia spectrum disorders identified 66% of the students who did not seek psychological treatment and had high scores on the Perceptual Aberration and Magical Ideation Scales as having an 8-6, 8-9, or a 9-8 MMPI-2 profile. Of the students who requested psychological treatment, 25% produced MMPI-2 schizophrenia spectrum profiles. Of these, 63% produced a 2-7-8 code profile. Additional analyses showed that only some of the students who requested psychological treatment and produced a 2-7-8 MMPI-2 profile exhibited schizotypal features and that this group stayed in therapy longer than students without schizophrenia spectrum profiles. These results suggest that only a subset of the students with high scores on the Perceptual Aberration and Magical Ideation Scales produce schizophrenia spectrum MMPI-2 profiles and that these profiles are substantially different from those produced by students with high scores on the Revised Social Anhedonia Scale and from schizotypal college students who seek psychological treatment.

Adult↗