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Biomedical subjects

D Zhang

Publications and source records attributed to D Zhang.

At least 685 records · Page 38Linked to original sources

Effects of the heat-tonification method on the surface temperature of the body observed by infra-red thermography.

With the infra-red thermography, 73 tests of the effect of Heat-Tonification maneuvers on body surface temperature were made. The experiments showed that application of Heat-Tonification produced marked elevation of temperature at the site of puncture, over the face and the front of the neck. The differences between pre- and post-needling temperatures were statistically significant (P less than 0.02 and P less than 0.01). Furthermore, 44.8% of the tests showed elevation of temperature over the trunk and extremities, and the distribution of temperature elevation followed the course of the meridians mostly. The findings demonstrated that the Heat-Tonification method mobilized Qi and activated Blood through influence over the vegetative nervous system that led to readjustment of blood circulation.

Acupuncture Therapy↗

Sinus node electrogram recording in complete atrioventricular block.

Surface electrocardiogram (ECG), sinus node electrogram (SNE), His bundle electrogram (HBE), and intracardiac electrogram of high right atrium (HRA) were recorded synchronously in 11 of the 14 consecutive cases with complete atrioventricular block (CAVB). SNE showed the presence of a pre-P wave that preceded in all the P wave on the ECG and had no relationship to QRS complex or TU repolarization. This confirmed that the pre-P wave arose from the sinus node. Direct sinoatrial conduction time (SACTd) in nine cases was within the normal range (less than 120 msec). SACTd in another two cases was prolonged to 185 msec and 210 msec, respectively, suggesting their abnormal sinus node conduction.

Adult↗

Bioavailability of total iron from meat, spinach (Spinacea oleracea L.) and meat-spinach mixtures by anaemic and non-anaemic rats.

1. Bioavailability of Fe from beef, spinach (Spinacea oleracea L.) and their mixtures was studied using anaemic and non-anaemic rats by haemoglobin regeneration efficiency (HRE) and apparent Fe absorption in two trials. 2. The initial haemoglobin levels of severely anaemic, mildly anaemic and non-anaemic rats were 63, 88 and 113 g/l, respectively. The Fe level in diets was about 30 mg/kg. All other nutrients equalled or exceeded the requirement of the growing rat. 3. The spinach Fe was well utilized by the rats with average HRE of 0.41, 0.53 and 0.36, and apparent Fe absorptions averaging 0.48, 0.59 and 0.37 for the severely anaemic, mildly anaemic and non-anaemic animals respectively. 4. Beef Fe was efficiently used by rats as reported by others. Average HRE were 0.42, 0.51 and 0.44, and average apparent Fe absorptions were 0.44, 0.47 and 0.46 for the severely anaemic, mildly anaemic and non-anaemic rats respectively. 5. When the percentage of meat Fe was increased from 0 to 25, 50, 75 or 100 of the dietary Fe, HRE and apparent Fe absorption were not increased significantly. A meat enhancement effect on total Fe absorption, reported by others for non-haem-Fe, did not occur in the present experiment. 6. Negative correlation coefficients between initial haemoglobin and HRE (r -0.79), and initial haemoglobin and apparent Fe absorption (r -0.73) were seen with the rats fed on dietary Fe from FeSO4.7H2O. This was not seen with the rats fed on dietary Fe from beef or spinach. 7. The Fe absorption pattern for the different Fe sources is evidence for a third Fe pool, a pool made up of highly soluble inorganic Fe salt, in addition to haem-Fe and non-haem-Fe complex pools. FeSO4.7H2O is not in the same gastrointestinal pool as non-haem-Fe complex such as spinach Fe. A suggested mechanism of absorption is discussed.

Absorption↗

Bioavailability of iron-milk-protein complexes and fortified cheddar cheese.

Iron fortification is used to increase dietary iron intake. Dairy products are widely consumed but contain almost no iron. Cheddar cheese was fortified with ferric chloride or iron-casein, ferripolyphosphate-whey protein, and iron-whey protein complexes. Hemoglobin regeneration efficiency was determined to evaluate iron bioavailability. Maximal and basal iron bioavailabilities were measured in anemic weanling rats fed low iron diets (about 22 mg iron/kg) and normal adult rats fed high iron diets (about 145 mg iron/kg) of iron density (32 mg iron/1000 kcal) found in some high iron human diets. Maximal iron bioavailabilities for ferric chloride or iron-casein, ferripolyphosphate-whey protein, and iron-whey protein complexes were 85, 71, 73, and 72%, respectively, and for the respective iron-fortified cheeses they were 75, 66, 74, and 67%. Differences were not significant in maximal iron bioavailabilities among iron sources and between fortified cheeses and fortification iron sources. Basal iron bioavailabilities for 10-d feeding of the respective fortification iron sources were 5, 8, 6 and 7%, respectively, and 4, 4, 3, and 3% for 14 d feeding; the differences among the iron sources were not significant. Maximal and basal iron bioavailabilities of ferrous sulfate were 85 and 5%, respectively. Practical implications of these observations are discussed.

Animals↗

[The distribution, characteristics and effects of ir-BNP in central and peripheral tissues in rat].

The present study first investigated the distribution, biochemical characteristics, receptor binding and biological effects of immunoreactive brain natriuretic peptide (ir-BNP), in the central nervous system and some peripheral tissues in rats, using highly specific radioimmunoassay, radioreceptor assay and immunohistochemical method. The results suggest that BNP may be a novel neurotransmitter or circulatory hormone, which is widely distributed in various tissues and involved in the regulation of water electrolyte balance and cardiovascular activity.

Animals↗

Missense Mutation in the Chlamydomonas Chloroplast Gene that Encodes the Rubisco Large Subunit.

The 69-12Q mutant of Chlamydomonas reinhardtii lacks ribulose-1,5-bisphosphate carboxylase activity, but retains holoenzyme protein. It results from a mutation in the chloroplast large-subunit gene that causes an isoleucine-for-threonine substitution at amino-acid residue 173. Considering that lysine-175 is involved in catalysis, it appears that mutations cluster at the active site.

Journal Article↗

Residual tactile sensitivity with self-directed stimulation in hemianaesthesia.

A case of hemianaesthesia caused by right hemisphere stroke was found to have good sensitivity and cutaneous localisation when she touched her impaired hand with her good contralateral hand or with a probe held by that hand. The capacity did not depend solely upon movement or positioning of her right arm, and she could also discriminate whether her own left fingers, as opposed to someone else's inter-digitated fingers, were being touched, but only when she did the touching. Thus, the threshold of the impaired hand appeared to be markedly affected by active involvement of the contralateral limb in delivering the stimulus.

Cerebral Cortex↗

Histone acetylation in chicken erythrocytes. Estimation of the percentage of sites actively modified.

Within the N-terminal regions of the DNA-bound histone, 26 lysine residues per nucleosome may be acetylated and deacetylated. In the present paper the percentage of these residues actively acetylated and deacetylated in chicken erythrocytes was measured. This percentage is estimated as 3.7% in chicken immature, and 2.1% in chicken mature, erythrocytes. In metabolically active, dividing, cells one would predict that, after a few generations, each site would at some point in time be modified. We conclude that, in the relatively inactive immature chicken erythrocyte, no more than 1-2% of the genome is composed of dynamically acetylated and deacetylated histone, this percentage decreasing with cell maturity. The active histone acetylation and deacetylation may be confined to transcriptionally active or potentially active erythrocyte domains.

Acetates↗

Interpregnancy weight retention patterning in women who breastfed.

This study compares weight change in lactating women with an 18-month interpregnancy interval with woman who also breastfed but did not have an immediate subsequent pregnancy. Cases were women who breastfed an index infant for 6 months and subsequently became pregnant within 18 months (cases = 25), and the controls also breastfed an index infant for 6 months but had no ensuing pregnancy (controls = 20) within 18 months. The pattern of postpartum weight retention following the initial pregnancy was not statistically different in cases compared to the controls. However, following their ensuing subsequent pregnancy, cases were 1.3 kg heavier than their average weight after their baseline pregnancy (P = 0.02). The best predictor of this greater weight was their weight change during the interpregnancy interval (P = 0.03). Total weight gain during the gestational period of the subsequent pregnancy was not associated with the greater weight following the subsequent pregnancy. Likewise, estimates of the amount of energy as calories or physical activity levels were not significant predictors of this greater weight following the subsequent pregnancy. These findings suggest that monitoring of postpartum weight, even in breastfeeding women, is essential. These findings indicate that breastfeeding women begin the next postpartum interval weighing more than the amount observed in the initial postpartum period.

Adult↗