Imidazo[1,2-a]pyrimidines as functionally selective GABA(A) ligands.
Imidazo[1,2-a]pyrimidines are GABA(A) receptor benzodiazepine binding site ligands which can exhibit functional selectivity for the alpha(3) subtype over the alpha(1) subtype. SAR studies to optimize this functional selectivity are described.
Imidazoles↗