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Biomedical subjects

E B Khaisman

Publications and source records attributed to E B Khaisman.

6 recordsLinked to original sources

Adrenergic terminal structures in the mesentery of mammals.

This work is devoted to the study of adrenergic terminal structures in the mesentery of mammals (cat, dog). The investigation was performed with the Falck-Hillarp method of catecholamine fluorescence microscopy on total stretch mesentery preparations. The investigation showed that richly developed perivascular plexus constitute the basis of the adrenergic innervation system of the mesentery. In numerous points of these plexuses, single adrenergic fibers or polyaxonal structures are observed to issue into nonvascular areas of the mesentery where after repeated dichotomic division they pass into the preterminal and terminal parts. Being constructed on the principle of extended or restrained arborizations, these innervating structures have a morphological similarity with free sensory nerve endings. In this connection, the question of the possible existence of the sensory (afferent) links in the catecholamine-containing vegetative nerve plexuses is discussed.

Adrenergic Fibers

The morphological phenomenon of paravascular reorganization of nerve conductors.

The work is devoted to the study of a peculiar morphological phenomenon called paravascular reorganization of nerve conductors. In its most general form this phenomenon takes the form of a flattening and an enlargement of the nerve bundles which surround the vessel in the zones of their paravascular localization. The nerve fibres undergo a number of morphological changes, the most characteristic of which are: proliferation of Schwann elements, foci of "demyelinization", varicose swelling of axons, mesh-like formations in the axis-cylinders. These changes are seen mainly in the myelinated fibres of afferent origin. The unmyelinated vegetative fibres remain unchanged in the zones of paravascular localization. The phenomenon of paravascular reorganization of the nerve conductors is of wide-spread occurrence in mammals and humans. It is found most often in flat organs and tissues whose thinness results in contiguity of blood-supplying vessels and nerve conductors. The role of vascular mobility as factor in the morphological reorganization of nerve conductors at their points of intersection and contact within the vascular walls is discussed.

Animals

Particular features of the innervation of taste buds of the epiglottis in monkeys.

The work is devoted to the study of the structure of the innervation apparatus of taste buds in the epiglottis of monkeys (Macacus rhesus). The Campos inpregnation method was used. It is established that several afferent myelinated fibers participate in the innervation of each taste bud of the epiglottis. The peculiarity of structure of their preterminal and terminal parts having the appearance of complex windings and spirals is noted. The polyaxonic principle of the innervation of taste buds of the epiglottis in monkeys is considered as a possible mechanism of generalization of the afferent impulses. It is suggested that the innervation apparatus of the taste buds of the epiglottis constitutes part of unique afferent system of this organ, ensuring its defensive function. The incongruity (from the histophysiological standpoint) of the term 'taste bud' in relation to the epiglottis is noted. It is proposed to call these formations special structures of the chemo-receptors.

Animals

An adrenergic component of the nervous apparatus of the aortic reflexogenic zone.

The structural organization of the adrenergic (sympathetic) component of the autonomic innervation of the depressor zone of the cat aortic arch was studied by luminescence microscopy of the catecholamines. A terminal adrenergic plexus, branching extensively in the connective-tissue basis of the depressor area of the aortic arch, was discovered. The participation of vessels supplying blood to the depressor area was established. Adrenergic neurons were found in the territory of the depressor zone of the aortic arch. It is postulated that the adrenergic component of the depressor zone of the aortic arch participates in the peripheral mechanism of the regulatory effects of the sympathetic nervous system on the baroreceptor apparatus.

Animals

A histochemical study of vegetative innervation of blood-vessels of serosa.

Research was carried out into the morphological substrate of the dual (sympathetic and parasympathetic) innervation of blood-vessels of the serosa, including the vessels of microcirculatory system. Tests were carried out on total preparations of the pericardium, pleura and peritoneum of dogs and cats. Using histochemical methods to show up adrenergic (Falck-Hillarp's method) and cholinergic (Koelle-Gomori's method) nerve structures the architectonics of both components of vasomotor innervation in various parts of the arterial and venous sytem of the serosa was described a gradient of their saturation with adrenergic and cholinergic innervation structures gradually decrease, the vessels branching out shown and entering the region of the terminal blood supply. Vegetative innervation of the precapillary arterioles and capillaries appears inconsistent and is mainly restricted to single synaptic contacts arising along the route of adrenergic and cholinergic terminals. In vessels of the venus system, including postcapillary venules and small collecting veins, vegetative innervation (adrenergic and cholinergic) invariably appears scanty and frequently can not be detected at all.

Acetylthiocholine