PubMed · 56761
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E K Pletchkova, E B Khaisman. 1976. Vegetative component of interoceptors.. https://doi.org/10.1016/s0079-6123(08)64339-3
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Highly purified acetylcholinesterases from various sources do not contain hydroxyproline and hydroxylysine, indicating the absence of a collagenlike 'tail'. The enzymes examined are therefore bound to the membrane in a different way compared with acetylcholinesterase isolated from electric organ.
X-irradiation of pregnant NMRI-mice on gestational days 11-13 with 3 x 10.5 Gy increased postnatal mortality of the female offspring only. Weights, protein content and acetylcholinesterase, as well as Na,K-ATPase activities in the brains of all treated offspring, were changed. There were, however, no differences between females and males with respect to these parameters.
Orchidectomy plus estradiol administration decreased acetylcholinesterase activity in the rat cerebral cortex and mesencephalon, while in the amygdala it was increased. In the adenohypophysis, orchidectomy increased enzyme activity, but subsequent estradiol treatment decreased it. The hypothalamus did not respond to either manipulation.