Development of Nil disease and focal segmental glomerulosclerosis (FGS) in sequential renal biopsies is reported in a patient with Hodgkin's lymphoma. Although steroid resistance was demonstrated, a complete and sustained clinical remission of the renal lesion followed anti-Hodgkin's chemotherapy. These findings support the hypothesis that Nil disease and FGS are manifestations of the same clinical entity.

Adult↗

PubMedDate not supplied

Cord care: too much or too little.

This research project was undertaken at a teaching hospital to determine whether no treatment of newborns' umbilical cords was more effective than the current treatment employed. One hundred and three babies were included in the study. The cords of babies nursed in one postnatal ward were not treated (trial group); babies nursed in another postnatal ward became the control group whose cords were treated with spirit (alcohol 70%) and ties. Cords separated earlier for the trial group (mean 6.4 days) than the control group (mean 8.04 days) and mothers of trial group babies reported fewer problems with umbilical cords than those of control group babies.

Female↗

PubMedDate not supplied

Prevention of hypokalemia caused by diuretics.

Hypokalemia induced by the use of diuretics is common. Those at risk include the elderly, women, patients with edematous states, and patients in whom higher doses and/or the more potent agents are used. Prevention should include a low-salt diet rich in potassium, magnesium, and chloride (either through foods enriched with these elements or through potassium chloride supplements) and use of low doses of short-acting diuretics in the treatment of mild to moderate hypertension. The subgroup of hypertensive patients in whom hypokalemia develops despite these recommendations may benefit from a change to the potassium-sparing diuretic spironolactone or substitution of diuretics with alternative first-line drugs.

Benzothiadiazines↗