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Biomedical subjects

E Challier

Publications and source records attributed to E Challier.

7 recordsLinked to original sources

Perirenal textiloma: MR and serial CT appearance.

We describe changes in imaging features of a textiloma (retained surgical sponge or retained foreign body) left in the renal fossa after exploratory renal surgery. One year after the initial surgery, the MR aspect of the textiloma was not specific, with a homogeneous low signal intensity on T1-weighted images. Serial CT examinations over 4 years demonstrated progressive growth and calcification of the mass which appeared pseudocystic with a peripheral inflammatory wall. Granulomas caused by a retained surgical sponge should be considered as a cause of retroperitoneal mass in patients with a history of prior surgery.

Adult

Lymph node metastases: safety and effectiveness of MR imaging with ultrasmall superparamagnetic iron oxide particles--initial clinical experience.

PURPOSE: To evaluate the clinical and biologic safety of ultrasmall superparamagnetic iron oxide particles (AMI-227) as a contrast agent for magnetic resonance (MR) lymphography and to assess their efficacy for the differentiation of metastatic and benign nodes in patients with urologic and pelvic cancer. MATERIALS AND METHODS: Thirty adults suspected of having lymph node metastases underwent MR imaging before and 22-26 hours after intravenous infusion of AMI-227 (1.7 mg Fe/kg). Sixty histopathologically proved lymph nodes were analyzed on MR images, and 29 of these nodes were also analyzed quantitatively. RESULTS: AMI-227 was well tolerated with no major side effects. It allowed the detection of 10 additional nodes relative to those detected at MR imaging without AMI-227. None of the 27 metastatic nodes showed a decrease in signal intensity (SI) on AMI-227-enhanced images; nine of 27 metastatic nodes showed an increase in SI on T1-weighted images, probably resulting from altered capillary permeability in the tumor. A visually perceptible reduction in SI, indicating active AMI-227 uptake, was observed on postcontrast T2- and T2*-weighted images in 16 of 21 benign nodes. The SI ratio of benign nodes was lower than that of metastatic nodes on T2- and T2*-weighted images. The sensitivity of AMI-227-enhanced MR lymphography was 100%, and the specificity was 80%. CONCLUSION: AMI-227 is safe and may facilitate the differentiation of metastatic and benign nodes in patients with urologic and pelvic cancers.

Adult

[Spontaneous intraperitoneal rupture of the ureter].

An unusual case of spontaneous intraperitoneal rupture of the ureter was observed in adult with acute renal pain. Diagnosis was best established with CT rather than intravenous urography. CT demonstrated ureteral leakage with the contrast medium extravasating into the peritoneal cavity. The patient was initially managed successfully by endourology. Secondary stenosis of the ureter required surgery for partial resection of the distal ureter.

Adult

[Imaging of small renal tumors].

The increased incidence of detection of small renal tumours, less than or equal to 3 cm in diameter, is related to the generalization and improvement of radiological techniques. Many asymptomatic renal tumours are discovered by ultrasonography and computed tomography. Medical imaging is now able to identify simple cysts (morphological characters, absence of blood supply), angiomyolipomas (demonstration of the fatty contingent) and other solid renal tumours (tumour enhancement on computed tomography). Plain, followed by postcontrast CT looking for contrast enhancement of the lesions is the examination of choice in this context. MRI with Gadolinium injection looking for neoplastic enhancement can be useful in doubtful cases. Medical imaging is able to reliably demonstrate the vascular nature of solid lesions, but cannot distinguish between renal cancer, oncocytoma or another benign solid tumour. Medical imaging allows precise preoperative mapping when partial nephrectomy is envisaged.

Adenoma, Oxyphilic

Ureteral stents: exchange under fluoroscopic control as an effective alternative to cystoscopy.

From September 1991 to February 1993, in 83 patients (74 women and nine men, aged 24-86 years), 166 double-J ureteral stents (initially placed to treat fistulas or stenoses located within the inferior third of the ureter) were exchanged during 127 procedures. Stents were extracted from the bladder through the urethra under fluoroscopic monitoring by using a lasso made of a 0.018-inch guide wire and a 7-F catheter. Then a new stent was placed over a 0.035-inch guide wire that had been previously coiled in the renal pelvis. Exchange was successful in 161 (97%) of 165 stents.

Adult

[MRI: overview, technique, interpretation].

The purpose of this paper is to describe the general principle of MRI, emphasising the practical conduct of the examination which consists of three main phases. The authors define the concepts of relaxation time and T1 and T2, essential parameters for the understanding of MRI. They simply explain how to recognise a predominance of T1- or T2-weighting on MRI images. They review the principal artefacts which must be recognised in order to avoid erroneous interpretation of the images. Lastly, they define the value of MRI in clinical urology, renal pathology, especially neoplastic, and prostatic and bladder disease.

Artifacts