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Biomedical subjects

E Chelo

Publications and source records attributed to E Chelo.

29 records · Page 2Linked to original sources
PubMedDate not supplied

Cervical cap homologous artificial insemination (AIH): the University of Florence experience.

We report our experience with artificial insemination with husband's semen (AIH) using cervical cap. Forty-four couples were admitted to our AIH program over a two-year period. In 4 couples, AIH was performed due to impotence or hypospadia, while in the remaining 40 couples indications for AIH were abnormal semen, poor post-coital test, anti-sperm antibodies, poor cervical mucus. Overall, six pregnancies were obtained (pregnancy rate = 15%) in the latter group; in particular, AIH was able to elicit pregnancy in 5 out of the 25 cases of abnormal semen (20%). Our data emphasize the importance of female factors associated with infertility since significantly higher pregnancy rates (45.4% versus 0%) were observed in subjects in whom these factors were absent.

Adult↗
PubMedDate not supplied

The imagined baby: the analysis of a desire.

Of the many people currently infertile, at least 40% have a problem related solely to the male. Feelings about infertility are based on something deeper and more engrained in a person's character called concepts. Concepts are formed by many forces such as religion, society, the value of others and so on. 61 males, partners of infertile couples, were invited to an interview using as a means of investigation a semistructured questionnaire. We focused our attention on the meaning these men gave to an eventual baby, and on the common opinion about a childless married man either from a social or an individual point of view. According to these criteria, we found that 42% of the people interviewed thought that "people" consider the lack of children as related to male impotence with remarkable differences between the opinion of those who lived in cities and those who did not. As for the solution prospected in the case of incurable sterility, 37% would chose to remain childless, a little lower percentage would choose a sperm bank and only 20% would choose adoption. The results of this research show that among many different aspects, the image of the baby for these applicant fathers is still linked to traditional values.

Adoption↗
PubMedDate not supplied

The MAR test as immunologic screening of male infertility.

The mixed antiglobulin reaction was developed for detection of platelet antibody and then modified to demonstrate antibodies on spermatozoa. We have used the test as a simple method of screening for antibodies in the male, performing the test during the analysis of semen samples. We evaluated 320 samples from partners of sterile couples attending our Sterility centers. The IgG MAR test was not applicable to 82 samples because the sperm concentration and sperm motility was not sufficient. In all uncertain, positive and firmly positive cases of MAR test and in 50 negative cases of IgG MAR test, as control group we performed MAR test for IgA. We correlate our results with the sperm test penetration, SCMC test and identification of antisperm antibodies test and Isojima test for sperm immobilizing antibodies. Our results reconfirm the utility of IgG MAR test as screening test for the presence of antibodies but its positiveness requires the performance of IgA MAR test and, if necessary, of other tests in order to diagnose sterility depending on immunologic factors.

Antibodies↗
PubMedDate not supplied

Plasma concentrations of FSH and testosterone in male infertile patients.

We studied the statistical distribution of the plasma concentrations of FSH and testosterone in patients with oligoazoospermia as compared with normospermic subjects. The plasma concentration of FSH was determined in 429 patients with oligoazoospermia and 282 normospermic subjects ("controls"). In 118 out of these 429 patients and in 47 of the 282 controls, the plasma concentration of testosterone was also measured. The plasma concentrations of FSH differed significantly depending on the patients' values of spermatic concentration. The most significant difference was observed between azoospermic patients and controls, whereas the difference between patients with mild oligospermia and controls was not significant. Conversely, the plasma concentrations of testosterone did not correlate with the values of spermatic concentration and even the difference between azoospermic patients and controls did not reach the significance level. In addition, testosterone plasma concentrations did not differ between two sub-groups of patients who were defined depending on whether the plasma concentration of FSH was normal or high. Our findings confirm the inverse relation between plasma FSH levels and spermatic concentration which had already been observed in previous studies. However, a considerable overlap in the plasma concentrations of FSH has been found between sub-groups of patients with different spermatic concentrations. This overlap limits the clinical usefulness of the measurement of FSH concentration inasmuch as normal FSH plasma levels may often be associated with any value of spermatic concentration. Also, our data confirm that the measurement of testosterone plasma levels provides little clinical usefulness in male infertile patients.

Adult↗
PubMedDate not supplied

Chronic phospholipid liposomes administration and ovarian function.

In the past years, hypothalamic phospholipids (H-PL) have been used therapeutically for their behavioral effects. The major pharmacological effect of H-PLs is that they increase the turnover rate of biogenic amines in the brain. Previous studies have also shown that a single i.v. dose of H-PL may influence tha plasma levels of gonadotropins, prolactin (PRL) and growth hormone (GH). Since data have not yet been published concerning the effects, if any, of chronic i.m. administration of H-PL on the ovarian function, the present study was undertaken to gain insight into this issue. Four women were studied. Each subject was given H-PLs by i.m. injection from the 5th to the 20th day of the cycle at the dose of 100 mg/day. Blood samples were repeatedly taken over this period to measure the plasma concentrations of FSH, LH, E2, PRL, and progesterone. GH administration, no side-effects were noted in any of the subjects studied. All subjects presented normal plasma levels of FSH, LH, E2, PRL, and progesterone. GH demonstrated some upward fluctuations, which always regressed rapidly. Our findings demonstrate that chronic H-PL administration at therapeutic doses does not influence the ovarian cycle in women. In the light of our data, it appears that different hormonal effects are elicited by a single i.v. high-dose administration of H-PLs as compared with those produced by chronic i.m. treatment at therapeutic doses.

Adult↗
PubMedDate not supplied

Dynamic echohysteroscopy: new perspectives for diagnostic sonography in female infertility.

Dynamic echohysteroscopy is a new diagnostic method which can be applied to the clinical problems of infertility, providing informations on the morphology of the internal genitals. The Authors underline the clinical validity of this diagnostic technique, even though more experience is required in order to define a better standardization of the method.

Fallopian Tube Diseases↗
PubMedDate not supplied

The response of serum and seminal plasma prolactin to bromocriptine in normal men.

The Authors describe their experience with a group of twelve volunteer healthy men in order to evaluate if the bromocriptine inhibition of serum prolactin concentration also modifies seminal plasma PRL values. The results of this study lead us to suppose that PRL in semen could arrive from serum by a filtration process through the prostatovescicular apparatus.

Adult↗