PubMed Health⌕ Search

Biomedical subjects

E Cronin

Publications and source records attributed to E Cronin.

At least 37 records · Page 2Linked to original sources

Dermatitis of the hands in caterers.

Hand eczema among 50 caterers was occupational in 47 and endogenous in 3 cases. Irritants were considered more important than sensitisers. There was a correlation between atopy and sensitisation to type-I but not type-IV allergens. The commonest type-I sensitiser was fish and for type-IV was garlic. Dilutions of garlic and of onion 50% in arachis oil were not irritant and seemed effective patch test materials. The prognosis was not good and the hand eczema continued even in some of those who changed their jobs.

Adolescent↗

Sensitivity to sunscreens.

The patients sensitised to sunscreen agents who attended our Contact Dermatitis Clinic between February 1985 to March 1987 have been reviewed. 15 (5%) of 280 patients tested with sunscreens had positive reactions; 3 of them were allergic to more than one agent. The most frequent contact allergens were hydroxy methoxy methyl benzophenone (Mexenone) [6], followed by isopropyl dibenzoylmethane (Eusolex 8020/8021) [5], octyl dimethyl para-aminobenzoate (Escalol 507) [2], and one reaction each to butyl methoxy dibenzoylmethane (Parsol 1789), amyl dimethyl para-aminobenzoate (Escalol 506), and ethoxy ethyl-p-methoxy cinnamate (Givtan F). Positive photopatch tests were seen with isopropyl dibenzoylmethane, butyl methoxy dibenzoylmethane, para-aminobenzoate (PABA) and ethoxy ethyl-p-methoxy cinnamate, one reaction each.

Benzoates↗

Photocontact urticaria from chlorpromazine.

Chlorpromazine is well recognized as a cause of delayed photosensitive eczema. A patient illustrated typical features of the phenomenon. Urticarial lesions were also elicited on photopatch testing.

Chlorpromazine↗

Clinical patterns of hand eczema in women.

The hand eczema of 263 women was studied as 4 clinical patterns: palms and fingers, dorsa and fingers, fingers only and the entire hands. The palmar pattern was the commonest. Sensitisers affected the patterns equally but irritants were of less significance in the palmar group than among the rest. Atopics did not appear to have a distinctive pattern. Among the occupational group, irritants were of much greater importance than allergens.

Allergens↗

Patch and photopatch testing in chronic actinic dermatitis.

Photopatch tests in 47 patients with chronic actinic dermatitis (CAD) showed musk ambrette to be the only significant allergen in our standard photopatch test series. The incidence of positive patch tests to a standard series of contact allergens in this group was compared with 213 men over the age of 50 years with eczema investigated in the contact clinic. Among the photosensitive patients, there was an increased incidence of reaction to thiuram-mix (CAD 10%; controls 3%), carba mix (CAD 6%; controls 1%), nickel sulphate (CAD 6%; controls 2%) and vioform (CAD 10%; controls 0.5%). A decreased incidence of reaction to potassium dichromate (CAD 0%; controls 8%) and balsam of Peru (CAD 4%; controls 10%) was recorded.

Adult↗

Photosensitivity to musk ambrette.

Photosensitivity to musk ambrette was confirmed in 15 men previously photopatch tested and in a further 4 men currently attending the clinic. 6 of the recalled patients continued to react adversely to sunlight due either to unrecognised exposure to musk ambrette or to their having become persistent light reactors. Positive photopatch tests, possibly cross reactions, were seen in 3 of the 19 patients with the structurally-related nitromusks, moskene and musk xylene but not with musks ketone and tibetine. Musk ambrette elicited a positive patch test without light in 3 of the 19 patients.

Acne Vulgaris↗

Antioxidants in cosmetics.

Antioxidants are commonly added to cosmetics. Allergy to these substances will be missed unless specifically looked for. During a 2-year period, patients with facial dermatitis have been routinely tested with butylhydroxyanisole and tertiary butylhydroquinone. 7 patients are reported who have been shown to have an allergic contact dermatitis to an antioxidant in their cosmetics or toiletries.

Aged↗

Lanolin of reduced sensitizing potential.

Confirmation has been obtained that reducing the content of natural free alcohols in lanolin to below 3%, particularly in the absence of detergent residues, reduces the incidence of positive patch test reactions amongst selected lanolin-sensitive skin patients by 99.3%. Only one reaction out of 149 subjects was recorded.

Alcohols↗

Allergy to phenyl salicylate.

Six cases of contact dermatitis from a lip salve are described. Five were allergic to phenyl salicylate and one to geraniol in the fragrance. The dermatitis spread in a ring around the mouth. Phenyl salicylate has been removed from the formulation.

Adult↗