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Biomedical subjects

E Grabbe

Publications and source records attributed to E Grabbe.

At least 181 records · Page 10Linked to original sources

Comparative study of suprapubic sonography and computed tomography for staging of prostatic carcinoma.

In addition to the digital rectal examination, suprapubic transvesical ultrasonography and computed tomography were used to stage local tumor extension in 41 patients with histologically proven prostatic carcinoma. Although 22% of the cases revealed stage A/B disease on rectal examination, these numbers were 7% for ultrasonography and 37% for CT. For stage C/D disease the percentages were 73% for digital rectal staging, 81% for sonography, and 30% for CT. Compared with the digital examination, 22% versus 10% of the cases had to be upstaged by the results of ultrasound versus CT. A downstaging became necessary by sonography in 7% and by CT in 44%. The results are compared with the findings after prostatectomy, autopsy, and cystoscopy as well as with pathohistological data from the literature. From these results, suprapubic transvesical sonography is considered to be more reliable than CT for local tumor staging.

Adult↗

[Digital subtraction angiography (DSA) in acute pulmonary embolism].

The results of 49 DSAs (in 29 patients) are presented; these were performed for the diagnosis or follow-up of pulmonary emboli. The direct or indirect signs of pulmonary emboli, known to occur during conventional pulmonary angiography, were used as diagnostic criteria. In 47 examinations it was possible to make or to exclude the diagnosis unequivocally. The advantages of DSA make it desirable to use this method as the first form of examination in the diagnosis of acute, but not immediately life-threatening, pulmonary emboli.

Adult↗

The perirectal fascia: morphology and use in staging of rectal carcinoma.

A revised anatomy of the perirectal fascia is proposed based on more than 2,000 CT examinations of the lower pelvis. CT examination showed that the perirectal fascia completely encloses the "capsula adipose rectalis" within the subperitoneal space and separates the perirectal compartment from the "pararectal connective tissue." The accuracy of CT in preoperative staging of rectal carcinoma was also demonstrated. It is concluded on the basis of 155 preoperative CT examinations of rectal carcinoma that CT staging is superior to Mason's clinical staging scheme, although routine staging by CT is not justified because slight perirectal tumor spread and lymph node metastasis cannot be predicted accurately.

Carcinoma↗

[Perforations during contrast enema].

During contrast enema, perforation into the retroperitoneal space can be differentiated from perforation into the peritoneum and perforation into the intestinal wall associated with formation of barium granulomas or submucosal spreading of the contrast medium. Other special forms are perforation with contrast medium embolism of diverticula; of the processus vermiformis; penetration of contrast medium into fistulous systems and from the operated area. Risk factors are: balloon catheter, intestinal tubes with a hard tip, preternatural anus, excessive enema pressure, contrast medium additions, preceding manipulations, intestinal diseases, advanced age and delegation of manipulations to assistants and unskilled staff. Children are particularly at risk.

Barium Sulfate↗

[Left-side changes in thoracic follow-up studies after heart surgery].

In routine thoracic x-ray follow-ups after cardiosurgical procedures, 93.2% of our patients (n = 88) showed radiologically perceivable pathological changes, reduced ventilation being the most common phenomenon. 77.1% the the patients showed signs of reduced ventilation, mostly the left side. Limited motility of the diaphragm on the left side was visible in 69% of the cases studied. The defective motility of the left diaphragm is attributable to direct damage to the left nervus phrenicus caused by extracardial heart cooling during surgery.

Cardiac Surgical Procedures↗

[Prognostic value of computed tomography in acute pancreatitis (author's transl)].

A prospective study was performed in 50 patients with acute pancreatitis to find out the value of computed tomography for an early prognosis. CT findings (retroperitoneal fluid collections with enlargement of the retroperitoneal space, intraperitoneal air-fluid levels and ascites), clinical (age, ileus) and laboratory tests (LDH, blood glucose, urea, creatinine and calcium) were taken into consideration. These data were collected during the first two days after hospitalisation and turned out to be of considerable prognostic value: About 70% of the patients died when 5 or more of these pathological findings existed. More than 90% of all patients who died belonged to this group.

Acute Disease↗

[The fascial planes round the rectum. Anatomic and computer tomographic correlations (author's transl)].

About 1000 patients mostly with rectal carcinomas but also with hematomas, abscesses and soft tissue tumors received CT-examinations of the posterior compartment of the pelvis before and after surgical treatment and radiation therapy. The morphology of the perirectal space is demonstrated under normal and pathologic conditions and can be compared with the current anatomical knowledge. Special attention has been focussed on the site of the so called "Hüllfaszien" or "Grenzlamellen" of the rectum and the division of the perirectal space. Nomenclature and description of the perirectal fasciae and spaces are somewhat controversial. Therefore misinterpretations of pathologic CT-findings are not uncommon.

Abscess↗

[Serial CT of liver - possibilities and limitations (author's transl)].

Dynamic computerized tomography (angio-CT or serial CT) has established itself quickly as complementary method to non-invasive liver examination methods. The article describes the requisite apparatus and examination method as well as the possibilities of evaluating the data obtained. Indication for serial CT should be critically assessed. The possibilities and limitations in interpreting local and time differences in the kinetics of the contrast medium bolus are demonstrated. In individual cases, serial CT offers valuable aid for the discovery of pathological findings at the large vessels and for differential diagnosis of focal liver lesions. On the other hand, it has gained little significance so far in diagnosing diffuse diseases of the liver parenchyma.

Adenoma↗