[Mediastinal widening in thoracic lordosis].
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Biomedical subjects
Publications and source records attributed to E Grabbe.
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A modified examination concept to improve conventional x-ray diagnostics in a intensive-care unit is presented. This planning is based on the development of new technical components in the field of mobile diagnostics and the availability of improved basic materials that can certainly promote such a project. This is presently being installed in the Clinical Centre of the University of Göttingen and will be subjected to a critical cost/efficiency analysis during a run of one year.
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Aftercare following surgery of colorectal tumours aims mainly at early detection of a relapse for the purpose of curative re-intervention. Improvement of diagnostic possibilities, especially by means of tumour markers, flexible endoscopy, computed tomography, magnetic resonance and ultrasound, increased the efficacy of aftercare; however, diagnosis of tumour recurrence has always been too late to perform repeated surgery with the expected measure of success. In relation to all cases of failure of therapy, the proportion of potentially curative re-interventions was about 10%. Whereas operations at the frame of the colon are practically free from a specific therapeutic co-morbidity, problems of continence may be expected in deep rectal surgery; especially after extirpation of the rectum, we can expect stoma problems and urogenital complaints as well as difficulties with the rectal excision wound. In case of adjuvant radiotherapy there may be irradiation sequels such as adhesion difficulties or radiogenic proctitis. The occurrence of metachronous secondary tumours is a special aspect of colorectal carcinomas, so that aftercare always includes prevention as well. Further aftercare measures follow from the context of psychosocial rehabilitation. Principally it is possible to achieve the ideal goal of complete reinstatement in the family, in society and in professional life after colorectal cancer surgery.
Gated images of patients with stronger pulsation artefacts in the brain stem were produced on a 1.5 tesla MR-imager, registering blood pulsations by means of a finger plethysmograph. A minimization of movement artefacts was achieved and thus sufficient diagnostic-value of images in these patients was noticeable. This gating method seems to be a promising simple alternative compared to the well known cardiac gating for imaging of the head and neck area. Its advantages and limitations are demonstrated.
Our experience of the effects of metallic foreign bodies on MRT high field examinations is described. In vitro measurements showed moderate magnetic torsion or displacement in a few cases. The findings in 60 patients with various metal foreign bodies and the resulting artifacts are discussed. Despite local loss of information, in the majority of cases there is additional evidence provided by MRT, which suffers less from foreign body artifacts than does CT. Stainless steel implants result in some signal loss and geometric distortion, but do not usually constitute a danger to the patient and do not affect the diagnostic information from surrounding structures.
After having used a 2 Tesla prototype whole body scanner for about one and a half years, it is now possible to comment on the clinical value of high field strengths. The methods and techniques employed are described. The problems arising from high field strengths are discussed and their effect on clinical diagnosis is indicated.
The authors present the case of a 61-year old man with microhematuria, in whom the preoperative diagnostic work-up (urography, percutaneous sonography, CT, retrograde pyelogram) had led to the diagnosis of a right sided renal tumour. Intraoperatively a kidney tumour was neither seen nor palpated. However, the mass was clearly outlined by intraoperative sonography. The following nephrectomy revealed an intrarenal adenocarcinoma of the kidney of 2.5 cm diameter.
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The authors reviewed 51 cases of local recurrence after sphincter-saving resection for rectal and rectosigmoid carcinoma to assess the sensitivity of current diagnostic procedures. A combination of follow-up serum CEA levels and rectoscopy was found to be most efficient during the first two years after surgery in terms of the time, frequency, and location of the recurrence as well as the cost-benefit ratio. On the other hand, almost all recurrent lesions developed extraluminally, infiltrating the suture line secondarily; moreover, one fourth extended outside the bowel wall. Thus in addition to endoscopy, CT is useful as a means of defining the entire mass at the anastomosis as well as detecting pericolic recurrence and is essential if repeat resection is contemplated.
The accuracy of CT in staging rectal carcinoma was examined on the basis of 172 preoperative CT-examinations of the pelvis. Especially in cases of advanced tumours CT was found to be superior to clinical staging as defined by Mason, except for low ventral tumour localisation. On the other hand, routine staging by CT is not justified because mesenteric lymph node metastases cannot sufficiently be predicted. The value of various diagnostic methods in detecting local recurrences was determined in 295 other patients after radical resection of the rectosigmoid due to carcinoma. Recommendations for effective follow-up studies of those patients are based on these results.
Involvement of visceral organs is a recognized condition of Reiter's Syndrome. To our knowledge, however, involvement of the colon, as it is seen in other rheumatoid-like processes mostly caused by vasculitis, has not been described before. We present the case of a patient with incomplete Reiter's Syndrome with arthritis, circinate balanitis and psoriasilike lesions of skin and nails who developed ischemic colitis. Angiographic features point to vasculitis as a potential cause, although this could not be proved. It is possible but, as we believe, unlikely that simultaneously administered steroid treatment may have contributed to the development of the lesions.
DSA is not suitable for the investigation of hepatic and splanchnic vessels by intravenous or non-selective arterial injections. On the other hand, its use in selective arterial injection offers many advantages compared with conventional arteriography. It can be particularly recommended for routine use in the pre-operative diagnosis of abdominal masses. In some cases additional conventional angiography may also be required and it is therefore desirable to perform both examinations at one unit in order to profit from the advantages of each technique.
In 241 patients examined for trauma of the skull by computed tomography, 36 fractures of the skull base were diagnosed, in addition to their intracranial lesions. Computed tomography demonstrated twice as many fractures as conventional radiography. Amongst surviving patients, 30% showed abnormalities which were directly related to fractures of the skull base. The type, complications and therapeutic consequences of skull base fractures are discussed. These observations show that the bony injury needs to be carefully considered in order to avoid extensive and time-consuming investigations which might otherwise become necessary later.
We examined the patency of aortocoronary venous bypasses in 51 patients during the early postoperative phase by using non-selective contrast injection into the aorta with digital subtraction angiography. In all patients it was possible to evaluate the degree of patency by this method. The accuracy and value of this examination, as compared with other invasive and non-invasive methods, is discussed.
Nineteen patients with various types of lipoma in the pelvis are described. Clinical findings, radiological examinations, and follow-up studies constitute a particular type of lipoma, diffuse infiltrating lipomatosis; this can be distinguished from other fatty tumours because of its localisation, extent, therapeutic results and long course. Computed tomography enables us to differentiate simple lipomatosis pelvis from diffuse infiltrating lipomatosis. Histological examination is essential for excluding a liposarcoma. Growth or malignant change of diffuse infiltrating lipomatosis is most easily recognized by computed tomographic serial observation.
Imaging and functional evaluation of the left ventricle are of great interest in cardiological diagnosis. So far, the left ventricle has been imaged by laevocardiography or by a nuclear medicine method (gated blood pool, first pass). The limited spatial and temporal resolution of nuclear methods and the invasiveness of selective laevocardiography are well known disadvantages of these techniques. With special software and hardware, it is possible to obtain functional images of the left ventricle by means of intravenous contrast injection; these provide definitive information concerning local myocardial contraction patterns.
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