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Biomedical subjects

E J Bell

Publications and source records attributed to E J Bell.

At least 55 records · Page 3Linked to original sources
PubMed1978

Stool viruses in babies in Glasgow 2. Investigation of normal newborns in hospital.

The stools of 37 newborn babies born in hospital were examined for the presence of virus. An extract of every stool passed by each baby was examined in the electron microscopy and inoculated into cell cultures. The babies were delivered in four separate maternity units (A-D). All the babies from unit A and C(9 babies) were found to be excreting rotavirus though none showed any evidence of diarrhoea. Two of the babies also excreted astrovirus. Subsequently unit A was closed for cleaning and, on reopening with more restrictions on visitors, a further 19 babies were examined. No virus was found in any of their stools, nor was virus observed in the stools of babies from units B and D, where visiting was also more restricted. Visiting restrictions in these units excluded older siblings of the babies. No virus was cultured from any stools in this study.

Environmental Exposure↗
PubMed1978

Role of Coxsackie B viruses in myocardial infarction.

Serological evidence of Coxsackie B virus infection was found in 13.5 per cent of 52 patients with acute myocardial infarction and in 19 per cent of 52 controls with chest pain but normal electrocardiograms. In contrast to an Australian report, but in agreement with previous findings in Glasgow, it seems unlikely that Coxsackie B viruses contribute significantly to the causation of myocardial infarction.

Adult↗
PubMed1977

Stool viruses in babies in Glasgow. I. Hospital admissions with diarrhoea.

Stools from 183 babies under 2 years of age admitted to Ruchill Hospital with diarrhoea were examined by electron microscopy, virus culture, bacterial culture and light microscopy. As far as possible, several stools were examined from each patient and the results showed rotaviruses, astroviruses and other viruses in association with symptoms, as well as the expected bacterial pathogens. Examination of several stools from the same patient also showed that in this age group the viral flora of the gut changes rapidly and that the viruses seen by electron microscopy were only rarely grown in cell culture and vice versa. This phenomenon was particularly noted with adenoviruses. In 30% of cases no microbial pathogen was identified and in the remainder the presence of the infecting organism did not always coincide with the symptoms. It is concluded that, with viruses at least, presence of the organism does not constitute proof of causation.

Adenoviruses, Human↗
PubMed1975

ECHO 9 infection in pregnant women with suspected rubella.

Both rubella virus and Echovirus 9 (ECHO 9) were epidemic in Scotland during the summer of 1973; both viruses can cause a mild febrile illness with rash. Sera from 286 rubella-negative pregnant women were tested for neutralizing antibodies to ECHO 9 virus; 40 women had antibody titres suggestive of recent infection. Prospective studies on the outcome of these pregnancies are in progress but preliminary results suggest no connexion between fetal damage and ECHO 9 infection.

Antibodies, Viral↗
PubMed1975

The epidemiology of enteroviruses.

International and local Scottish data illustrate the epidemiology of enteroviruses in recent years. Polioviruses still predominate as causes of serious paralytic disease, except where controlled by vaccination and require continuing surveillance. Aseptic meningitis is the commonest reported illness due to enterovirus infection, but notable clinical manifestations of certain types (particularly coxsackie group A) involve the skin and mucous membranes and the respiratory tract. Gastrointestinal disturbance has been reported in some echovirus infections, and cardiac disease is particularly associated with group B coxsackie virus infections. Although most enterovirus infections are silent or trivial in severity, the trend towards periodic epidemicity of different enteroviruses involving older age-groups may entail the emergence of new disease problems of which heart disease may be one example.

Adult↗
PubMed1975

Echovirus type 4 infections in Scotland, 1971-72.

An outbreak of infection due to echovirus 4 in Scotland involving 194 cases during 1971-72 is described. Clinical and epidemiological information was obtained and analysed for 181 patients, of whom 149 (82%) developed aseptic meningitis. The majority of cases were older children (39%) and young adults (40%), although the highest attack rate was in infants (10.5 per 100,000 population). An unusual feature of the outbreak was its biphasic nature with cases occurring largely in the same geographic areas in successive years.

Adolescent↗
PubMed1974

Epidemic keratoconjunctivitis in the West of Scotland, 1967-72.

Outbreaks of epidemic keratoconjunctivitis have occurred among workers in shipyards and other industrial concerns in the West of Scotland in 1956, 1967 and 1971-72. In the most recent episode 220 persons were known to be affected and those mainly involved were shipyard personnel working on the open decks of ships under construction; only a few non-industrial workers were affected. As in previous outbreaks adenovirus type 8 was shown to be the causal organism. It is likely that spread of the virus was probably facilitated in some of the patients by such procedures as first aid measures to remove foreign bodies from the eye. A survey of the family contacts of those affected in 1971-72 revealed that only 2% were secondarily infected. This was probably due to propaganda measures to discourage the use of communal face towels, etc.Despite close virological surveillance over a period of 6 years of patients attending opthalmic clinics in the West of Scotland, there is as yet no clue to the whereabouts of adenovirus type 8 during interepidemic periods. It is suggested that travellers might be responsible for the introduction of the infection into an area.

Adenoviridae↗
PubMed1974

A six-year study of coxsackievirus B infections in heart disease.

Virological examination of 385 patients with suspected heart disease and 26 with Bornholm disease over a period of 6 years suggested that Coxsackie group B virus infections were associated with at least half the cases of acute myocarditis and one third of the cases of acute non-bacterial pericarditis. Complement-fixation tests revealed only a few cardiac illnesses associated with other infections (influenza and Mycoplasma pneumoniae). No evidence of infection was found in chronic cardiac disease.

Adolescent↗