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Biomedical subjects

E Krokowski

Publications and source records attributed to E Krokowski.

At least 37 records · Page 2Linked to original sources

[Cancer prophylaxis: gain or risk? (author's transl)].

One of the most important measures for the improvement in curative cancer therapy, stagnant during 25 years, will be a cancer prophylaxis as extensive, intensified and directed as possible. Seventy percent of all the cancerous diseases are produced by seven cancer species. Of these seven species, four are appropriate for a promising cancer prophylaxis: the mammary, uterine and intestinal catzinoma in women, the intestinal carcinoma in men. Risks as well as improvements concerning prophylaxic examination for cancer of the breast or prostatic carcinoma are discussed in detail.

Adult↗

[Are the actual criteria of tumor classification and therapy valuation sufficient for the tumor therapy? (author's transl)].

The classical notions of tumor diagnosis (classification and diagnostic accuracy) as well as the generally accepted criteria for evaluating the success of the tumor therapy (mortality graphs, survival time and remission) are submitted to a critical examination. It is found that the actual version of these notions and criteria can cause serious errors in diagnosis and valuation. It seems therefore indispensable to complete and correct these generally used notions. However important scientifically founded and precisely defined parameters for tumor therapy and its valuation may be, one must never forget on the other hand that the treatment of a tumor patient is an individual problem and that the most important task of the oncologist remains to give psychological guidance to every single patient.

Humans↗

[Does cancer therapy program its failure, too? (author's transl)].

Is seems indispensable, in consideration of the present investigation results, to revise our actual therapeutic conception for cancer therapy! While palliative cancer therapy was greatly successful, it was not possible to obtain any decisive improvement of cancer recovery rates (in relation to similar stages or tumor volumes), in spite of all the therapeutic endeavour through the last twenty or twenty-five years. From almost 3000 analyses of metastatic growth and from numerous other experimental or clinical observations results as an explication that surgical treatment itself, on certain conditions, may release a relatively great number of metastases. Thus, the failure of our therapeutical endeavor is programmed, too, by the treatment! Consequences for diagnostics, precautions and therapy are discussed.

Aged↗

[Contrast-free radiological diagnosis of the skull (author's transl)].

From the broad spectrum of contrast-free radiological diagnosis of the skull, diseases with asymmetrical appearance of the face were selected and the syndromes similar to them are presented from the differential diagnostic point of view. Asymmetry of the head very frequently indicates a disease of the skull area and should be subjected to appropriate diagnostic investigations.

Adult↗

[Muscular insufficiency as a partial cause of osteoporosis. Significance for therapy (author's transl)].

Osteoporosis as a disease is more than a mere development of porosity of the bone. Between the axial skeleton and the musculature of the trunk there are mutaual relationships affecting circulation, metabolism and function which become active in the genesis and development of an osteoporosis. For this reason, therapy must not only be directed towards reossification of the bony skeleton, but also to the elimination of muscular insufficiency and improvement of the functional capacity of the musculature of the trunk.

Bone and Bones↗

[Interpretation of the x-ray signs of osteoporosis as special aspect of the new haemodynamic biostatic theory of osteoporosis (author's transl)].

Based on the author's new haemodynamic biostatic theory of osteoporosis the typical symptoms of osteoporosis are demonstrated by X-ray, revised, interpreted and completed. Atrophy of trabeculae related to osteoporosis, consequences for vertebrae bodies and vertebrae column are chronologically explained. Introduction and distribution of force are discussed and the special importance of muscular system and discs to maintain supporting capacity is emphasized.

Biomechanical Phenomena↗

[A new theory of the etiology of osteoporosis (author's transl)].

A new theory of the etiology of osteoporosis--inaugurated by the author and developed in cooperation with Fricke--is step by step elaborated and explained. Alteration of the bone marrow is observed simultaneonly with osteoporosis--caused by reduced blood flow in bone and bone marrow, and promoted by reduced muscle work, i.c. inactivity, influencing blood circulation in bone and bone marrow. Alteration of statics and vertebral bodies resulting from bone atrophy and reduced muscular force are newly interpreted by a new theory capabilities of radiological osteoporosis-diagnostis are preceding.

Absorptiometry, Photon↗

[Patterns of localization and process in age induced bone atrophy and pathological osteoporosis (author's transl)].

Dennert and Münzenberg recommend comparative examination of x-rays of the spine and coxal end of the femur both for the differentiation of physiological bone atrophy and pathological osteoporosis and for the gradual evaluation of osteoporosis. The systematic bone deterioration in the proximal section of the femur in physiological osteoporosis is absent in the pathological forms of osteoporosis where only the skleletal trunk is usually involved. Since quantitative examination procedures for the exact differenciation of osteoporosis are generally not available for the practice, the comparative examination represents an essential help for diagnosis and the gradual evaluation of osteoporosis. To support the interpretation of the findings from this procedure which is well suited for the practice, the chronological and local process of physiological and pathological osteoporoses (obtained by quantitative radiological measurements) are compared.

Adult↗

[Sociomedical significance and restabilization therapy of osteoporosis (author's transl)].

Osteoporosis (physiological or pathological) is to be expected in about 7 million citizens of the Federal Republic. Fracture-promoting osseous atrophy, vertebral deformities limiting movement for maintenance of stability and skeletal pains due to muscular weakness and change of posture are the symptoms which frequently lead to disability. When osteoporosis turns to a disease in this way, then sodium fluoride therapy is recommended for reossification and restabilization of the bones. Prophylactically, for reduction of osteoporosis over the age of 40, light gymnastics, regular swimming and the avoidance of noxae which decrease the blood flow are to be advised.

Adult↗

[Osteoporosis- more than a bone disease (author's transl)].

Neither the bone-matrix theory of osteoporosis established by Albright in the 1940's nor the lack-of-calcium theory of the 1960's especially represented by Nordin, due to experimental tests and clinical results could be maintained. Here a new theory of osteoporosis is introduced, explaining osteoporosis not to be primarily a disfunction of calcium- or bone metabolism, but as a part-symptom of disfunction of the whole sustentaculum -bones, marrow, nucleus pulposus and musculation. Osteoporosis is predisposed by amyothenia respectively in activity and is initiated by reduced blood circulation of the sustentaculum. Certain relevant conclusions for prophylaxis and therapy of osteoporosis can be deduced without neglecting already the presently only effective therapy using sodium fluoride.

Adrenal Cortex Hormones↗

[Osteoporosis -- due to reduced blood circulation of bone (author's transl)].

According to a theory of the authors both senile osteoporosis and pathologic osteoporoses (rheumatic, in diabetes, bronchial asthma, pulmonary emphysema, portal hypertension and Cushing's disease) are due to disturbances of the circulation of the blood in bone. Every type of stasis in the sinusoids, be it due to reduced arterial supply or venous stasis or to a reduction of extravascular fluid-pressure will provoke an increase in osteoclastic activity and thus osteoporosis.

Adult↗