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E Leidig

Publications and source records attributed to E Leidig.

23 records · Page 2Linked to original sources
PubMed1980

[Disturbed postoperative course in the treatment of necrotizing enterocolitis (NEC) (author's transl)].

The necrotizing enterocolitis (NEC) is marked by three stages, each of which has characteristic clinical symptoms and radiological findings. The management and prognosis are different in each stage. The experiences we got from 27 patients, seen in 5 years, are demonstrated and the typical postoperative complications are analysed. The conclusion can be reached that NEC has the best prognosis by a conservative treatment in stages I and II, and that a surgical approach is indicated when stage III turns into stage IV.

Child↗
PubMedDate not supplied

[Noninvasive, continuous monitoring of artificial respiration in premature and newborn infants by the constant measurement of respiratory minute volume, oxygen consumption and carbon dioxide release].

A system of instrumentation for the continuous measurement of the respiratory gases during assisted ventilation of neonates and premature infants based upon "breath-by-breath-method" is described. The four respiratory parameters flow (V), ventilation pressure (p), oxygen-concentration and carbon dioxide-concentration are measured. These datas are processed by a computer to generate a continuous display of the respiratory minute volume, the tidal volume, the breath rate, the oxygen consumption and the carbon dioxide production. All parameters are stored and can be displayed or plotted as trends. The flow-measurement is performed using hot-wire-anemometry. The very small flow sensor is adapted directly to the tube. Next to this sensor, the respiratory gas for the analysis of the O2- and CO2- concentration is suctioned off continuously. First clinical experience in mechanically ventilated newborns is characterized.

Carbon Dioxide↗
PubMedDate not supplied

[Pregnancy monitoring and labor planning in PLA1-induced neonatal alloimmunothrombocytopenia].

Alloimmune thrombocytopenia in newborns may lead to severe bleeding. Most often this thrombocytopenia is caused by incompatibility in the PlA system (mother PlA1 negative, child PlA1 positive). If the mother produces antibodies against PlA1 which cross the placenta, they will then destroy the child's platelets. Recent investigations have shown a strong correlation between HLA-DR3 and production of antibody. Since no screening for such antibodies is performed during pregnancy the resulting thrombocytopenia in the newborn will always be a sudden event. The best therapy is transfusion of PlA1 negative platelets; if no PlA1 negative donor can be found (2.25% of all donors) platelet concentrates of the mother may be used. After diagnosis of PlA related thrombocytopenia the relatives of the mother should be tested for PlA for the following reasons: 1. to determine PlA1 negative relatives to be used as possible donors in future pregnancies, and 2. to detect PlA1 negative women of child bearing age. If pregnant these women should be HLA-DR typed and followed for anti PlA1 antibodies to estimate the risk for the child and to determine further procedures, for instance sectio caesarea to avoid intracranial bleeding during birth.

Adult↗