Effects of nicotine fading and relapse prevention on smoking cessation.
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Biomedical subjects
Publications and source records attributed to E Lichtenstein.
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Modeling influences on adolescent smoking behavior were investigated. Twenty-eight male and twenty-eight female teenagers were exposed to each of three experimental conditions: a male smoking confederate, a female smoking confederate, and no model present. The order of each of these half-hour long conditions was counterbalanced across subjects. Three aspects of smoking behavior were directly observed: number of cigarettes smoked, number of puffs per cigarette, and duration of each cigarette. The presence of a smoking model increased the number of people who smoked and the number of cigarettes smoked and decreased the number of puffs per cigarette. The sex of the model did not affect the smoking behavior of either male or female subjects. Boys tended to smoke more cigarettes than girls (p less than .06) and boys took significantly more puffs per cigarette than did girls in the model present conditions. The results provide experimental confirmation that modeling influences teenagers' smoking behavior, but the rate of smoking in the absence of a model demonstrates that modeling effects cannot account for the maintenance of smoking.
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Somatostatin (SRIF)-like immunoreactivity was localized in the central visual pathway of near-term prenatal rats using light-microscopic immunocytochemistry and a highly specific antibody to the peptide. SRIF was demonstrable in neuronal perikarya and fibers of the lateral geniculate nucleus, superior colliculus and visual cortex. At this stage the distribution of these elements had not attained the pattern seen in the adult. The presence of SRIF in the central visual pathway prior to maturation suggests a role for this peptide in the development of visual function.
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Diabetes insipidus (DI) and other features of hypothalamic dysfunction were observed in two patients resuscitated following cardio-respiratory arrest (CRA). Both patients also developed marked hyperglycemia probably related to hypertonic dehydration. The development of DI in survivors of CRA suggests severe hypothalamic hypoxic injury and poor prognosis.
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