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E Martuscelli

Publications and source records attributed to E Martuscelli.

45 records · Page 3Linked to original sources
PubMed1980

[Hypertrophic obstructive cardiomyopathy associated with significant coronary artery stenosis. Apropos of 2 cases. Diagnostic and therapeutic considerations and review of the literature].

Hypertrophic obstructive cardiomyopathy (HOCM) is rarely associated with significant coronary artery stenosis. Differential diagnosis may be difficult because of similar symptoms; therefore we suggest coronary arteriography in all patients above 30 years of age having HOCM and angina associated. Obviously, in case the clinical diagnosis is coronary artery occlusive disease, left ventriculography is mandatory to rule out HOCM. Four medical treatment beta-blocking agents are the drugs of choice associated, if needed, with coronary dilators, avoiding nitrates. In case surgical treatment is selected, complete correction of all lesions is indicated.

Adrenergic beta-Antagonists↗
PubMedDate not supplied

Correlation between angiographic success and functional improvement assessed by exercise test following percutaneous transluminal coronary angioplasty.

Sixty-one consecutive patients with stable effort angina and single vessel disease underwent successful (reduction of coronary stenoses by greater than or equal to 20%) percutaneous transluminal coronary angioplasty (PTCA). Anatomical results were analysed on the basis of functional evaluation obtained by exercise test (ET) 1 week before (pre-PTCA) and within 1 month after (post-PTCA) PTCA. Total exercise duration and maximal double product significantly increased after PTCA (4.5 +/- 1 min vs 6.9 +/- 1.5 min, p less than 0.001 and 14.1 +/- 3.6 x 1000 mmHg x bpm vs 18 +/- 4.2 x 1000 mmHg x bpm, p less than 0.001). Pre-PTCA ET was positive in 43 patients (70%) and post-PTCA ET in 15 (24%). In patients with post-PTCA positive ET, mean stenosis diameter reduction was significantly lower than that obtained in patients with negative post-PTCA ET (29.6 +/- 8.9% vs 61.1 +/- 18.8%, p less than 0.001). In conclusion, PTCA improved exercise tolerance in the majority of patients with myocardial ischemia, however the definition of anatomical success used in this study appears to be poorly correlated with functional improvement as assessed by ET.

Angioplasty, Balloon, Coronary↗