Biomedical subjects

E Merz

Publications and source records attributed to E Merz.

96 records · Page 6Linked to original sources

PubMedDate not supplied

Mathematical modeling of fetal limb growth.

Using ultrasound measurements of the femur, tibia, humerus, radius (N = 515), and fibula and ulna (N = 385) from normal fetuses between 12 and 40 completed weeks of gestation, growth models were determined for each bone by computer analysis. On the basis of residual analysis, growth of fetal limb bones could best be expressed as a function of tangens hyperbolicus. Growth profiles and growth data are shown with 5th, 10th, 50th, 90th, and 95th percentiles. These results are compared with previous investigations of limb bone measurements.

Bone and Bones↗

PubMedDate not supplied

Prenatal diagnosis of infantile neuronal ceroid-lipofuscinosis: a combined electron microscopic and molecular genetic approach.

Based on two unrelated index patients afflicted with INCL, fetal chorion tissues were studied from subsequent pregnancies of the two respective mothers resulting in the prenatal diagnosis of INCL in two of the three pregnancies. Documentation of INCL was based on electron microscopy and DNA studies of the biopsied chorion tissue, later confirmed in the two affected fetuses after termination of their pregnancies by demonstrating INCL-specific lipopigments in post-mortem tissues, in the liver of both aborted fetuses and, additionally, in spleen and skeletal muscle of one of the affected fetuses. The autolysis of the aborted tissues, however, precluded a systematic documentation of all affected cell types and tissues. Thus, prenatal diagnosis of INCL is feasible and reliable for both Finnish and non-Finnish families.

Abortion, Induced↗

PubMedDate not supplied

[Prenatal ultrasound findings in Arnold-Chiari deformity].

The Arnold-Chiari malformation is a congenital deformity characterized by displacement of parts of the cerebellum, fourth ventricle, pons and medulla oblongata into the spinal canal. The ACM almost always is associated with a hydrocephalus and a myelomeningocele. The report demonstrates the sonographic findings of a ACM at 20 weeks' gestation. Clinical findings, aetiology and pathogenesis of the malformation are discussed.

Acetylcholinesterase↗

PubMedDate not supplied

[Syndrome of the absent umbilical cord in ultrasound].

A case is presented of complete aplasia of the umbilical cord with concomitant severe anomalies of the fetus at 19 week's gestation. The sonographic findings are demonstrated and the pathogenesis of this rare malformation is discussed.

Abdominal Muscles↗

PubMedDate not supplied

[Thanatophoric dwarfism - prenatal diagnosis of a fatal form of osteochondrodysplasia using ultrasound].

The report presents the ultrasonographic diagnosis of thanatophoric dwarfism in the 33rd week of pregnancy. This congenital osteochondrodysplasia is characterized by a relatively large head, a narrow thorax, a protuberant abdomen and micromelic limbs, and hydramnios is often present. The early diagnosis of this lethal malformation allows the obstetrician to decide on the appropriate way of delivery.

Bone Diseases, Developmental↗

PubMedDate not supplied

[Ultrasound imaging of the symphysis fissure for evaluating damage to the symphysis in pregnancy and postpartum].

In a cross-sectional study of 211 patients with a normal pregnancy the distance of the symphysis was sonographically measured during pregnancy and normal values were evaluated. Physiologically a continuous widening of the symphysis was shown up to 3 mm an average. The sonographical sign of the damage of the symphysis was a deviation in widening and also a difference in height. The value of the sonographic examination is shown in 2 cases with damage of the symphysis and compared to the x-ray picture results.

Adult↗