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E Morrison

Publications and source records attributed to E Morrison.

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Dietary protein and lead retention.

The effects of dietary protein content on lead retention were studied in young rats. In experiments lasting between 3 and 6 weeks, rats given diets containing lead and 20% casein were fed ad libitum or were pair fed with rats given diets containing 6.5 or 7.5% casein. Among rats given 20% casein, lead retention was inversely related to growth rate. A reduction of dietary protein either had no effect or reduced lead retention. In other experiments lasting 4 days and using 203Pb, given orally or intraperitoneally, the recovery of isotope in the gutfree carcass was unaffected or reduced by a reduction in dietary protein. Blood and liver lead often increased when kidney and carcass lead decreased in response to a reduction of dietary protein. Conflicting observations on the effect of low-protein diets on lead retention may thus be due to opposing effects of low dietary protein and decreases of growth rate and to different responses of different tissues.

Animals↗

The effect of age on the absorption and excretion of lead.

The retention (the proportion of ingested or administered lead found in the carcass at slaughter) of lead in the carcass and tissues of rats given 203Pb intraperitoneally or by mouth was measured over a period of a few days at 3-month intervals for 9 months from weaning. Total carcass retention of 203Pb administered intraperitoneally reached a minimum at 6 months of age, but the retention of 203Pb in blood, liver, and kidney changed little with time. When 203Pb was given by mouth, the fraction of the dose absorbed and the fraction retained in the carcass reached a minimum at 6 months, but the recovery in the tissues continued to decrease up to the end of the experiment. The addition of 20 mg of lead/kg of diet had no consistent effect on the metabolism of 203Pb.

Absorption↗

Crude craftsmen.

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Egypt↗