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Biomedical subjects

E N Nesterov

Publications and source records attributed to E N Nesterov.

At least 37 records · Page 2Linked to original sources

[Anisakiasis in the Caspian seal].

On the basis of 548 helminthological dissections the main foci of Anisakis infection of Caspian seal and the character of pathomorphological process in the stomach infected with the nematode Anisakis schupakovi have been established.

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[Pancreatic kallikrein, a protector of small intestine damage in post-ischemic toxemia].

The morphofunctional state of the small intestine was studied on a tourniquet shock model. The development of postischemic toxemia is followed by disorders of microcirculation leading to irreversible changes in the small intestine. The processes are associated with an increase of the proteolytic activity of the intestinal contents. An oral administration of andecaline prevents ischemia of the intestine, contributes to the preservation of its mucosa.

Animals↗

[Change in the antiradical activity of surfactant lipids during the development of nonspecific inflammatory processes in rabbit bronchopulmonary tissue].

Content of total lipids, phospholipids and cholesterol was estimated in surface-active fraction isolated from rabbit lungs. The surface activity and antiradical properties were decreased in the fraction simultaneously with a decrease in phospholipid contents in the course of development of inflammatory process in bronchopulmonary tissue. These data suggested that the antiradical activity, which is essential for protection of the surface-active fraction against free radical peroxidation, was mainly due to the phospholipid component.

Animals↗

[Effect of kontrikal on the activity of proteolytic enzymes and their inhibitors in blood, state of the bronchoalveolar secretion and the nature of the lung damage in dysenteric intoxication].

The development of dysenteric intoxication in rabbits led to an abrupt increase in the blood activity of proteolytic enzymes. This increase was accompanied by the reduced content of alpha 1-antitrypsin, and that of rapid and slow kallikrein inhibitor. Meanwhile there occurred a remarkable decrease in blood serum ability to bind chymotrypsin and kallikrein, and diminution of alpha 2-macroglobulin level. Trypsin, binding by blood serum did not undergo any substantial changes. In these conditions, the permeability of pulmonary vessels drastically rose and surface activity of the washing off dropped. The pathomorphological alterations in the lungs corresponded with the appearance of the "shock lung". Contrykal normalized the blood content of proteolytic enzymes and inhibitors, as well as that of the bronchoalveolar washing off, averted the development of gross pathomorphological alterations, exerting no appreciable effect on the surface activity of the bronchoalveolar washing off.

Animals↗