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Biomedical subjects

E Olszewski

Publications and source records attributed to E Olszewski.

At least 19 recordsLinked to original sources

[The efficiency of surgical treatment of patients with malignant tumors of nasal cavity and paranasal sinuses].

In the years 1966-80, 96 patients with malignant tumors of nasal cavity and paranasal sinuses were surgically treated in the Department of Otolaryngology, Medical University in Cracow. Out of 29 patients with macro and microscopic radical surgical treatment, 11 (37.9%) survived 5 years. The remained 62 patients, considering non-radical surgical treatment, have been additionally treated by full course of irradiation. Out of this group 34 (54.8%) survived 5 years. These data suggest that indications for additional irradiation should be extended.

Carcinoma

[A simple method of the vocal cord laterofixation].

Six patients were treated by the new method of vocal cord latero-fixation which was the combination of the extra-laryngeal and intra-laryngeal approach. The functional contraindication for this procedure is the anatomic configuration of larynx.

Adult

[Chronic granulomatous otitis media with irregular symptoms].

In the ENT Department, Medical Academy of Cracow, the patient with tinnitus synchronized with pulse as a first symptom of chronic granulomatous otitis media was treated. The diagnosis was made on the basis of the CT examination. The tympanoplasty was successfully performed.

Adult

[Metastatic tumors of the orbit].

The authors described patients with metastatic tumors, treatment in 1985-1990 year in Otolaryngologist Department Medical Academy in Kraków and dealing with the diagnosis and treatment. It is usually easy treatment the patients with orbital tumors but is very difficult when the orbital tumors are metastatic neoplasms of the orbita.

Female

[One stage reconstructive surgery of the hypopharynx from clinical material of the ENT Clinic Medical Academy in Cracow].

From April 1990 till September 1991 in ENT Clinic Medical Academy in Cracow 6 patients with well advanced laryngeal cancer involving hypopharynx were treated surgically. Total laryngectomy with partial or total hypopharyngectomy was performed and then the reconstruction of hypopharynx one stage procedure using pectoralis major myocutaneous flap was done. In all patients cosmetic and functional results were excellent.

Humans

[Non-epithelial malignant neoplasms of the larynx].

Among total number of 1399 patients with laryngeal malignant tumors treated in Cracow Otolaryngological Clinic in the years 1966-1985 there were only six (4%) patients with non-epithelial neoplasms. These patients were operated upon by various types of laryngectomy.

Adolescent

[Analysis of the causes of failure in surgical treatment of cancer of the larynx].

In the years 1985-1990 within the group of 2769 patients operated upon for laryngeal cancer in four medical centres (Kraków, Poznań, Warszawa, Lublin), a clinical analysis on surgical treatment failures was performed. The most significant reasons of failures were: the highly advanced age of patients, coexistent diseases, in particular the cardiopulmonary disease; poor information of neoplastic diseases (carcinomas) and delayed referral to the doctor; lack of consent for surgical treatment; old fashioned diagnostic methods; prolonged period of making diagnosis; increasing number of patients with supra-glottic localization including the hypo-pharynx and piriform recess; a considerable degree of organ ++cancer advancement and substantial clinical advancement; not radical excision of neck glands; intra-surgical blood transfusion; micrometastases to lymphatic glands; immunity collapse; discontinuance of post-surgical radiation on affected parts; lack of lymphadenectomy backward from accessory nerve ; massive cancer metastases to lymph nodes; high histologic malignancy with characteristic carcinous invasiveness; and finally, surgical and post-surgical early and late complications ranginy within our material from 25% to 29% of surgical patients. Basing on the above mentioned analysis, the authors developed indications for surgical treatment of laryngeal cancer.

Age Factors

[Evaluation of the effectiveness of surgical treatment of metastases of laryngeal cancer to the lymph nodes].

The evaluation of surgical treatment results was done to 308 oncological patients to whom metastases were formed in lymph nodes between 1980-1984, following the previous surgical treatment of the laryngeal cancer. The evaluation included among others the following: cancer initial localization: T and N traits; the degree of malignancy; surgical radical intervention ; assertion of neoplastic cell plugs in vessels; the time of recurrent lymphatic metastases, etc. The efficiency of surgical treatment of metastases being formed following the previous surgical treatment of laryngeal cancer, measured by the time of 5 years asymptomatic life, equalled 33.4% in the discussed material. Moreover, it was stated that in the studied group of 308 patients the percentage of deaths was increasing in the subsequent years of taking observations (from 1980 to 1984) and depended also on patients overall condition, initial cancer localization, the degree of neoplastic advancement and on the degree of cancer histologic malignancy.

Adult

[Evaluation of the causes of lymphatic metastases after surgical treatment of patients with laryngeal cancer].

During the years 1980-1988 2458 laryngeal cancer patients were operated upon in 4 ENT AM Clinics in Kraków, Poznań, Lublin and Warszawa. 300 (12%) out of them have had the cervical node metastases in 18 months after the surgery. The cause analysis was performed. The primary localizations were in the epiglottic and ++post-cricoid areas. The causes of metastases to the ++lymph nodes were analyzed; the primary epiglottic and ++post-cricoid localization of the tumor, its extensiveness and advanced clinical stage. Twice more often were the nodal metastases stated before the primary treatment, a high degree of histological malignancy, probably insufficient radicality of the surgery and insufficient immunological resistance of the organism were taken in consideration. This group of patients presented a rather high percentage of early unsuccessful results of surgical treatment of the laryngeal cancer; this problem needs further analysis and observations.

Adult

Results of laryngeal cancer surgery in four ENT centers in poland.

The results of laryngeal cancer surgery were assessed in a group of 832 patients treated in four major ENT centers in Poland. Five-year survival rates were as follows: stage I, 86%; stage II, 71%; stage III, 54%; and stage IV, 42%. In experienced hands and for properly selected cases, cure rates after partial (conservation) laryngeal surgery were similar to those after total laryngectomy. For early stages (I and II), the survival after partial surgery was better than that found after radiotherapy.

Adult

[Evaluation of complications after surgical treatment of cancer of the larynx].

The surgical complications in a group of 1712 laryngeal cancer patients treated during the years 1981-87 in ENT Clinics of Cracow, Poznań, Warsaw and Lublin were described. The most dangerous were bleedings and the most frequent wound and tracheo-+-bronchial infections and pharyngo-cutaneous fistulas++, after radical neck dissection however the paralysis of sublingual and accessory nerves and of brachial plexus. The predisposing factors were: diabetes, lung and heart diseases, late stage of cancer, extent of surgery and tumor infections.

Adult

SEM observations on the cellular transmigration through the wall of blood vessels in cancer of the human larynx.

Human larynges, removed surgically for advanced planoepithelial carcinoma were used for study. After employing appropriate preparation procedure the obtained material was examined in scanning electron microscope (SEM). The predominant findings were: the human cancer cells transmigrate through the venule lining at/or near the sites of the endothelial intercellular junction, capillaries and postcapillary venules constitute a territory within the transmigration of lymphocytes, piercing the body of the endothelial cell, occur in both directions, the cellular elements of the immune system are relatively more numerous gathered in the peripheral areas of the primary tumor, the obtained results are consistent with in vivo and in vitro experimental data.

Carcinoma

Bronchial asthma and pathological processes in the nasopharynx. I. Clinical analysis during remission and attack.

In 54 patients with bronchial asthma and a control group of 15 subjects laryngological, bacteriological and cytological examinations of the nasopharynx were performed. This region was found to be inflamed in 38% of the patients with asthma; in a group of asthmatic patients hypersensitive to aspirin, the percentage rose to 87%. In the asthmatic patients, as compared with the control group, there was a diminished neutrophilic exudate, a marked epithelial desquamation reaction and an abundant lymphocyticosinophilic exudate in a considerable percentage of cases.

Adult