Biomedical subjects
Publications and source records attributed to E Rosario.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The observation that severe clinical bacterial infections are associated with decreases in total serum albumin levels was confirmed in experiments involving dogs and rats. In rodents, the injection of methylprednisolone sodium succinate after the onst of the infection significantly reduced the decrease in the serum albumin values. However, this protective or corrective effect did not occur if the steroid was given prior to the infection. The effect of cortisone may be due to its capacity to stimulate albumin synthesis by the parenchyma of the liver.
Explore the source record for details and available documents.
Rats, weighing 125-150 gm., were restrained under a tight wire screen for one hour at 20degrees C and another hour at 4degrees C of ambient temperature. Animals receiving no infusions, or those receiving an intravenous solution of normal saline, developed 16 +/- 3 S.D. bleeding areas in their gastric mucosa. In contrast, in animals exposed to the same degree of stress who received intravenous hyperalimentation, the number of gastric stress bleeding areas counted was 4 +/- 2 S.D. These results demonstrate that the delivery of calories and protein in the form if intravenous hyperalimentation can significantly reduce the incidence of gastric stress bleeding in an experimental model (P less than .001).
Explore the source record for details and available documents.
The injection of barium sulphate (micropaque) contaminated with Staphylococcus aureus into the nutrient artery of the canine tibia produced typical inflammatory bone changes. This alteration, similar to those observed in human hematogenous osteomyelitis, consisted of medullary destruction, spontaneous fractures, and intense periosteal new bone formation. This system seems to mimic the characteristics of some clinical bone infections and may provide a model for therapeutic trials.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.