Dedifferentiated chondrosarcoma of humerus with giant cell tumor-like features.
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Biomedical subjects
Publications and source records attributed to E T Habermann.
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The importance of early, secure, internal fixation in the management of pathologic fractures, especially if bone stock has been severely compromised, is clearly recognized by the orthopedic surgeon. There is virtually no place for denying surgical treatment to the majority of these cases, because it would most probably leave them in a painful, bedridden state. The risks of operative intervention and the use of methylmethacrylate along with fixation devices are justified when analyzing the end results of relief of pain, ambulatory activity, and restoration of function, as well as psychologic benefits. The use of radiotherapy and chemotherapy along with surgery has greatly enhanced the management of this disabled patient population. Fracture healing can take place in the presence of extensive destructive lesions. Survival rates are improving and earlier recognition of skeletal metastasis by newer technology, including bone scanning and computerized axial tomography, is helpful in the overall management of these patients. The goals of treatment can be achieved by proper planning and a multidisciplinary approach to the patient with metastatic skeletal disease.
An unusually rare case of chondrosarcoma arising from an osteochondroma of a finger is presented. Chondrosarcomas of the hand in general are rare and almost always central in origin. Malignant degeneration of previously known enchondromas can occur and account for some but not all cases of chondrosarcoma of the hand. Histologic interpretation of cartilagenous lesions of the hand is difficult, and clinical behavior and radiographic appearance and appearance at surgery are often more reliable indicators of malignancy. Clinical suspicion should be aroused in an older individual with a previously quiescent lesion that becomes larger and/or more symptomatic. The clinical course of these tumors is slow and metastasis is late and usually to the lungs. Treatment of choice is amputation or ray resection of the affected part. Prognosis is good if metastasis has not occurred.
The elderly patient may be significantly benefited by careful evaluation and treatment of lower extremity disease. A great deal of emphasis must be given to preoperative planning to assure the most predictable outcome of any treatment program. Arthritis about the major joints has been revolutionized joint replacement surgery and fracture treatment has undergone many changes in the elderly. Most elderly patients can undergo surgical intervention.
Since the initiation of maintenance dialysis and renal transplantation, the course of patients with chronic renal disease has been altered. One of the frequent complications found in such patients is the development of secondary hyperparathyroidism, which is commonly associated with metastatic calcification and a variety of bone lesions collectively referred to as renal osteodystrophy. Bilateral rupture of the quadriceps tendon is a rare complication and previous reports have prescribed surgical correction of the ruptured tendon. The present case is that of a patient on chronic hemodialysis with secondary hyperparathyroidism and bilateral spontaneous rupture of the quadriceps tendon who was treated successfully without surgery.
Computed tomographic (CT) guided biopsy and abscess drainage of multiple organ systems have been well described. Reports of spinal and skeletal applications have been less common. This study describes the use of CT guidance in the biopsy of various skeletal lesions in 46 patients. Forty-one patients had skinny needle aspirations (18 or 22 gauge) and 23 patients had trephine core biopsies. Sites of the lesions included: thoracic spine-15 patients, lumbosacral spine-17 patients, bony pelvis-6 patients, rib-2 patients, and long bones-6 patients. Fast scanners capable of rapid image reconstruction have overcome many constraints. With CT guidance, the physician who performs the procedure receives virtually no ionizing radiation. The exact location of the needle tip is accurately visualized in relation to the lesion being biopsied and to the vital organs.
The entrapment of a foreign body within a dislocated hip prosthesis is an unusual occurrence. Dislodgement of the fragments by closed reduction should be attempted to try to extricate the fragment from the femoral head and acetabular cup interface. If closed techniques prove unsuccessful, arthroscopy can be used to guide instrumented removal of the interposed fragments.
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The bacterium Hemophilus influenza, also known as the Pfeiffer bacillus, is generally regarded as a disease of infancy and early childhood. An occurrence in adulthood is rare. A 43-year-old woman developed septic arthritis of more than one joint caused by Hemophilus influenza. The infrequency of this infection and the degree of difficulty in diagnosis is confirmed by a review of the literature.
Two hundred eighty-three pathologic fractures and 23 impending fractures of the hip and femur were analyzed and compared after surgical treatment. One hundred ninety-six fractures were treated by internal fixation or prosthetic replacement and the adjunctive use of methylmethacrylate, and 110 were treated by surgery without the use of methylmethacrylate. Pain relief, ambulatory activities and survival rates were all enhanced in the methylmethacrylate group. The six failures of fixation in the nonacrylic group might have been prevented by the use of bone cement. Breast carcinoma was the most common metastasis, comprising 56% of the series. Kidney metastases, when treated aggressively, showed many long-term survivors. Lung metastases gave the worst prognoses. The overall series survival rates were 59% at six months and 48% at 12 months. The incidence of complications including infection were not related to the use of methylmethacrylate or preoperative radiation. Although many authors have reported the advantages of methylmethacrylate in stabilization of pathological fractures, none have compared the results by analyzing pain relief, ambulatory ability and survival times in those treated with and without bone cement. This study appears to clearly indicate that methylmethacrylate enhances the stability of the pathological fracture and contributes to achieving the goals of treatment in these severely compromised patients.
In order to evaluate the effect of microaggregate blood filtration on pulmonary status, hemostatic status, and incidence of infection, a prospective study was performed on patients undergoing elective total hip replacement for osteoarthritis. Forty patients were randomized to either a 260 micron standard filter group or a 20 micron microaggregate filter group. Patients were monitored pre- and postoperatively for changes in arterial blood gases and in vitro test of hemostasis. Postoperative measurements were also made of the total volume of blood collected from the operative wound drain and of the number of infections incurred by patients in the two filter groups. Average transfusion was 4.0 units for the standard filter group and 4.6 units for the microaggregate filter group. Results showed that postoperatively, either immediately or after 48 hours, there were no statistically significant differences (p greater than 0.05) between either filter group for any of the tests of pulmonary or hemostatic function evaluated. For infection no trends were found to suggest that microaggregate filters conveyed any protective effect. These data suggest that routine microaggregate blood filtration of up to 5 units of blood is not required.
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