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Biomedical subjects

E Traub

Publications and source records attributed to E Traub.

At least 55 records · Page 3Linked to original sources
PubMed1977

[Changes of the blood gases following the application of naloxon (author's transl)].

74 patients, undergoing gynaecological operations under neuroleptanesthesia were subdivided into 4 groups, each receiving Naloxone in different doses postoperatively. For a longer period of time tidal volume, respiratory rate, minute ventilation, blood gas volues and pain index were recorded. From the results one can conclude that 0.1-0.2 mg Naloxone i.v. seems to be the most effective dose to reverse opiate-induced respiratory depression. The initial i.v. dose should be followed by an i.m. dose of 0.2 mg, if required.

Blood Gas Analysis↗
PubMed1977

[Apgar status, blood gases and acid base balance of neonates after caesarean sections, using either thiopentone or ketamine for induction of anaesthesia (author's transl)].

Apgar status and acid base balance of 206 neonates, delivered by caesarean section under general anaesthesia, were investigated in order to compare the possible effects of either thiopentone- or ketamine-induction on the postpartum adaption. Several other criteria were recorded also, for instance, a possible neonatal asphyxia, the induction-delivery-interval, the maternal age, the administration of other than anaesthetic drugs etc. There were not correlations between the Apgar status and the induction-delivery interval in either groups. The number of neonates within the 3 Apgar-classes, and the asphyxiated neonates, were equally distributed in the thiopentone- and ketamine-groups. There was no correlation between maternal ages and either the thiopentone- or ketamin-babies, but a marked correlation with the number of depressed newborns. Those neonates, who were suspected to be hypoxic before anaesthesia showed a more depressed post-partum respiration after thiopentone- than after ketamine-induction. On the other hand it seems to be that neonatal respiration and total Apgar status was more depressed if the "ketamin mothers" were treated with sedatives, hypnotics and/or analgesics before caesarean section. The blood gas values and the acid base parameters did not show a statistically significant difference between the pH of the thiopentone- and the ketamine-neonates. These differences can be explained as the combination of the nonsignificant changes in PCO2 and standard-bicarbonate values. As far as can be judged from the above mentioned criteria it may be deduced that ketamine or thiopentone can equally well be used for inducation of anaesthesia for caesarean section.

Acid-Base Equilibrium↗
PubMed1977

[Clinical studies on analgesia in obstetrics using intravenous administration of droperidol and pethidin (author's transl)].

In 70 healthy women under labor, the clinical properties of the combination DHB (0,1 mg/kg) and Pethidin (0.4 mg/kg) was studied for analgesia purposes in obstetrics; on request, Pethidin was given repeatedly. The fallowing conclusions can be drawn from this study: 1. The recommended "analgesic mixture" of DHB and Pethidin i.v. in the above mentioned doses is usually without harm to mothers and fetuses or new born respectively. 2. The Pethidin dosage, used in this study, agrees with the doses, recommended in the literature (0,4 mg/kg/h). 3. There was no difference between I-para, II, III-para etc., as far as the Pethidin requirement are concerned. 4. The analgesic properties of the mixture, judged by using clinical criteria only, were not quite convincing. This may be due to an increase of the intensity of uterine contractions by the mixture itself.

Adult↗
PubMed1976

[Clinical studies on the use of ketalar in obstetric anesthesia (author's transl)].

26 healthy pregnant women at term were divided into 2 groups and anaesthetized with either 1 mg/kh or 2 mg/kg ketamine - N20/02 - for primary caesarean section. Maternal venous ketamine plasma levels, neonatal ketamine plasma levels (umbilical artery and umbilical vein) and blood gases were measured. Maternal venous ketamine plasma levels in group I exceeded those in group II by 2.8 (30-60 sec after injection) and 2.0 (at the time of delivery) respectively. Independent of the dose used, the plasma levels of ketamine in the umbilical artery or the umbilical vein were found to be identical in the two groups of newborn infants. Neonatal blood gases and acid base parameters did not significantly differ between the two groups, except for the oxygen tension in group II which slightly exceeded the PO2 values in group I 15, 60 and 120 min after delivery. pH and standard bicarbonate values were found to be higher (1 and 5 min) in both groups, compared to pH and standard bicarbonate levels in a group of newborns delivered spontaneously.--The results of this study show: 1. Independent of a low or high ketamine dosage, neonatal blood concentration of the drug remain low, probably due to a placental barrier effect.--2. The post partum recovery of the newborns was neither influenced by the ketamine anesthesia itself nor by different drug doses.

Anesthesia, Obstetrical↗