Biomedical subjects

E Van der Eycken

Publications and source records attributed to E Van der Eycken.

2 recordsLinked to original sources

PubMed2001

Asymmetric induction in intramolecular meta photocycloaddition: cyclodextrin-mediated solid-phase photochemistry of various phenoxyalkenes.

[reaction: see text]. An approach to the asymmetric intramolecular meta photocycloaddition of phenoxyalkenes is described. The beta-cyclodextrin complexes of several phenoxyalkenes have been synthesized and irradiated in the solid phase. The effect of the CD-hosting on the regio- and enantioselectivity is discussed. Values of ee up to 17% were obtained.

Alkenes↗

PubMedDate not supplied

Efficient Pd(0)-mediated microwave-assisted arylation of 2-substituted imidazo[1,2-a]pyrimidines.

A short and practical synthesis of 2,3-substituted imidazo[1,2-a]pyrimidines, based on microwave-assisted Heck-type arylation of 2-substituted imidazo[1,2-a]pyrimidines, was developed. A 45-membered library of 2,3-substituted imidazo[1,2-a]pyrimidines was obtained with good yields and purities using this optimized protocol.

Catalysis↗